One size does not fit all: Lysosomes exist in biochemically and functionally distinct states.

Single-organelle resolution approaches have the potential to advance our knowledge of the heterogeneity of lysosome function. Challenging population-based models, we propose a "lysosome states" concept that links single lysosomes to function.

Informations de copyright

Copyright: © 2024 Bussi, Gutierrez. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

We have read the journal’s policy and the authors of this manuscript have the following competing interests: MGG is an Academic Editor at PLOS Biology.