Infantile atopic dermatitis - increasing severity predicts negative impacts on maternal and infant sleep: a mixed methods study.

Atopic dermatitis Infant sleep Maternal sleep Mixed methods Sleep disturbance

Journal

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
ISSN: 1710-1484
Titre abrégé: Allergy Asthma Clin Immunol
Pays: England
ID NLM: 101244313

Informations de publication

Date de publication:
22 Mar 2024
Historique:
received: 16 10 2023
accepted: 28 02 2024
medline: 23 3 2024
pubmed: 23 3 2024
entrez: 23 3 2024
Statut: epublish

Résumé

While the impacts of atopic dermatitis (AD) on maternal and child sleep outcomes have been previously explored, less is known about the associations between infantile AD and sleep quality and quantity. To describe the perceived causes of AD-associated maternal sleep disturbances and the association between AD severity and infant sleep outcomes. Mothers with infants aged < 19 months old with a diagnosis of AD were recruited from social media and medical clinics in Winnipeg, Canada between October 2021 and May 2022. Infant AD severity was classified using maternal-reported data on the Patient-Oriented Scoring Atopic Dermatitis tool (PO-SCORAD). Quantitative data were collected via a series of questionnaires with a subset of mothers subsequently completing semi-structured interviews. Quantitative and qualitative data were integrated in the discussion. Mothers of infants with moderate/severe AD (6/12) were more likely to report their infant suffering from a higher degree of sleeplessness (i.e., ≥ 5 on a scale of 0-10) over the past 48 h compared to mothers of infants with mild AD (0/18). This was supported by qualitative findings where mothers described how their infant's sleep quality and quantity worsened with AD severity. Additionally, 7/32 mothers reported that their child's AD, regardless of severity, disturbed their sleep. Maternal sleep loss was most commonly attributed to infant itching (6/7), followed by worry (4/7). Infantile AD severity was associated with worse sleep outcomes for both mothers and infants. We propose that maternal and infantile sleep quality and quantity can be improved by reducing AD severity through adherence to topical treatments.

Sections du résumé

BACKGROUND BACKGROUND
While the impacts of atopic dermatitis (AD) on maternal and child sleep outcomes have been previously explored, less is known about the associations between infantile AD and sleep quality and quantity.
OBJECTIVE OBJECTIVE
To describe the perceived causes of AD-associated maternal sleep disturbances and the association between AD severity and infant sleep outcomes.
METHODS METHODS
Mothers with infants aged < 19 months old with a diagnosis of AD were recruited from social media and medical clinics in Winnipeg, Canada between October 2021 and May 2022. Infant AD severity was classified using maternal-reported data on the Patient-Oriented Scoring Atopic Dermatitis tool (PO-SCORAD). Quantitative data were collected via a series of questionnaires with a subset of mothers subsequently completing semi-structured interviews. Quantitative and qualitative data were integrated in the discussion.
RESULTS RESULTS
Mothers of infants with moderate/severe AD (6/12) were more likely to report their infant suffering from a higher degree of sleeplessness (i.e., ≥ 5 on a scale of 0-10) over the past 48 h compared to mothers of infants with mild AD (0/18). This was supported by qualitative findings where mothers described how their infant's sleep quality and quantity worsened with AD severity. Additionally, 7/32 mothers reported that their child's AD, regardless of severity, disturbed their sleep. Maternal sleep loss was most commonly attributed to infant itching (6/7), followed by worry (4/7).
CONCLUSION CONCLUSIONS
Infantile AD severity was associated with worse sleep outcomes for both mothers and infants. We propose that maternal and infantile sleep quality and quantity can be improved by reducing AD severity through adherence to topical treatments.

Identifiants

DOI: 10.1186/s13223-024-00883-x PMID: 38519963
pubmed: 38519963
doi: 10.1186/s13223-024-00883-x
pii: 10.1186/s13223-024-00883-x
doi:

Types de publication

Journal Article

Langues

eng

Pagination

21

Subventions

Organisme : Research Manitoba
ID : Research Manitoba

Informations de copyright

© 2024. The Author(s).

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Auteurs

Zoe Harbottle (Z)

Department of Pediatrics and Child Health, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Children's Hospital Research Institute of Manitoba, 501G-715 McDermot Avenue, Winnipeg, MB, Canada.
Department of Food and Human Nutritional Sciences, Faculty of Agricultural and Food Sciences, University of Manitoba, Winnipeg, MB, Canada.

Amanda Nötzel (A)

Karolinska Institutet, Stockholm, Sweden.

Michael A Golding (MA)

Department of Pediatrics and Child Health, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Children's Hospital Research Institute of Manitoba, 501G-715 McDermot Avenue, Winnipeg, MB, Canada.

Manvir Bhamra (M)

Department of Pediatrics and Child Health, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Children's Hospital Research Institute of Manitoba, 501G-715 McDermot Avenue, Winnipeg, MB, Canada.
Department of Food and Human Nutritional Sciences, Faculty of Agricultural and Food Sciences, University of Manitoba, Winnipeg, MB, Canada.

Isac Kopsch (I)

Karolinska Institutet, Stockholm, Sweden.

Erik Wilking (E)

Karolinska Institutet, Stockholm, Sweden.

Marina Jonsson (M)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Centre for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden.
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.

Elissa M Abrams (EM)

Children's Hospital Research Institute of Manitoba, 501G-715 McDermot Avenue, Winnipeg, MB, Canada.
Department of Pediatrics and Child Health, Section of Allergy and Clinical Immunology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

Michelle A Halbrich (MA)

Department of Pediatrics and Child Health, Section of Allergy and Clinical Immunology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.

Elinor Simons (E)

Children's Hospital Research Institute of Manitoba, 501G-715 McDermot Avenue, Winnipeg, MB, Canada.
Department of Pediatrics and Child Health, Section of Allergy and Clinical Immunology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Children's Allergy & Asthma Education Centre, Health Sciences Centre Winnipeg, Winnipeg, MB, Canada.

Leslie E Roos (LE)

Children's Hospital Research Institute of Manitoba, 501G-715 McDermot Avenue, Winnipeg, MB, Canada.
Department of Psychology, Faculty of Arts, University of Manitoba, Winnipeg, MB, Canada.

Jill A Keddy-Grant (JA)

Department of Pediatrics and Child Health, Section of Dermatology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.

Thomas V Gerstner (TV)

Department of Pediatrics and Child Health, Section of Allergy and Clinical Immunology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.

Jo-Anne St-Vincent (JA)

Children's Allergy & Asthma Education Centre, Health Sciences Centre Winnipeg, Winnipeg, MB, Canada.

Sandra Ekström (S)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Centre for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden.
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.

Jennifer L P Protudjer (JLP)

Department of Pediatrics and Child Health, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada. Jennifer.Protudjer@umanitoba.ca.
Children's Hospital Research Institute of Manitoba, 501G-715 McDermot Avenue, Winnipeg, MB, Canada. Jennifer.Protudjer@umanitoba.ca.
Department of Food and Human Nutritional Sciences, Faculty of Agricultural and Food Sciences, University of Manitoba, Winnipeg, MB, Canada. Jennifer.Protudjer@umanitoba.ca.
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Jennifer.Protudjer@umanitoba.ca.
George and Fay Yee Centre for Healthcare Innovation, Winnipeg, MB, Canada. Jennifer.Protudjer@umanitoba.ca.
ORCID: 0000-0002-3888-8688

Classifications MeSH