Cervical ripening balloon compared with vaginal dinoprostone for cervical ripening in obese women at term: A prospective cohort study.
cervical ripening
cervical ripening balloon
maternal morbidity
neonatal morbidity
obesity
vaginal delivery
vaginal dinoprostone insert
Journal
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
ISSN: 1879-3479
Titre abrégé: Int J Gynaecol Obstet
Pays: United States
ID NLM: 0210174
Informations de publication
Date de publication:
22 Mar 2024
22 Mar 2024
Historique:
revised:
04
03
2024
received:
23
01
2024
accepted:
09
03
2024
medline:
23
3
2024
pubmed:
23
3
2024
entrez:
23
3
2024
Statut:
aheadofprint
Résumé
To evaluate vaginal delivery in obese women who underwent cervical ripening at term using a dinoprostone vaginal insert or a cervical ripening balloon (CRB), and to assess maternal and neonatal morbidity according to the method. A prospective cohort study including obese women with a live singleton fetus in cephalic presentation who required cervical ripening at term (≥37 weeks) for maternal and/or fetal disease using a dinoprostone vaginal insert or a CRB. The primary outcome was vaginal delivery. Secondary outcomes were a favorable cervix (Bishop score >6) after 24 h, the time from device insertion to delivery, and composite maternal and neonatal morbidity. In total, 135 consecutive women were analyzed (107 CRB, 79.3%; 28 dinoprostone vaginal insert, 20.7%). Vaginal delivery (86 [80.4%] after CRB vs 19 [67.9%] after dinoprostone vaginal insert; P = 0.248), favorable cervix within 24 h after device placement (52 [48.6%] vs 17 [60.7%]; P = 0.264), and maternal morbidity (12 [11.2%] vs 4 [14.3%]; P = 0.646) were similar between the groups. The time from device insertion to delivery also did not differ between the groups. Neonatal morbidity was significantly higher after the dinoprostone vaginal insert (11 [39.3%] vs 20 [18.7%]; P = 0.030). Cervical ripening using the dinoprostone vaginal insert, compared with the CRB, was significantly associated with neonatal morbidity (adjusted odds ratio 4.00, 95% confidence interval 1.34-12.5), but not with maternal morbidity (adjusted odds ratio 1.23, 95% confidence interval 0.30-4.38). Vaginal delivery, a favorable cervix after 24 h, the time from device insertion to delivery, and maternal morbidity did not significantly differ between the CRB and the dinoprostone vaginal insert for cervical ripening in obese women at term. Nevertheless, neonatal morbidity was significantly associated with the dinoprostone vaginal insert, compared with the CRB, among obese women who required cervical ripening at term.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024 International Federation of Gynecology and Obstetrics.
Références
O'Dwyer V, O'Kelly S, Monaghan B, Rowan A, Farah N, Turner MJ. Maternal obesity and induction of labor. Acta Obstet Gynecol Scand. 2013;92:1414‐1418.
Wolfe KB, Rossi RA, Warshak CR. The effect of maternal obesity on the rate of failed induction of labor. Am J Obstet Gynecol. 2011;205(128):e1‐e7.
Pevzner L, Powers BL, Rayburn WF, Rumney P, Wing DA. Effects of maternal obesity on duration and outcomes of prostaglandin cervical ripening and labor induction. Obstet Gynecol. 2009;114:1315‐1321.
Thorsell M, Lyrenas S, Andolf E, Kaijser M. Induction of labor and the risk for emergency cesarean section in nulliparous and multiparous women. Acta Obstet Gynecol Scand. 2011;90:1094‐1099.
Dai RX, He XJ, Hu CL. Maternal pre‐pregnancy obesity and the risk of macrosomia: a meta‐analysis. Arch Gynecol Obstet. 2018;297:139‐145.
Santos S, Voerman E, Amiano P, et al. Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta‐analysis of European, North American and Australian cohorts. BJOG. 2019;126:984‐995.
Hermesch AC, Allshouse AA, Heyborne KD. Body mass index and the spontaneous onset of parturition. Obstet Gynecol. 2016;128:1033‐1038.
Denison FC, Price J, Graham C, Wild S, Liston WA. Maternal obesity, length of gestation, risk of postdates pregnancy and spontaneous onset of labour at term. BJOG. 2008;115:720‐725.
Jozwiak M, Oude Rengerink K, Benthem M, et al. Foley catheter versus vaginal prostaglandin E2 gel for induction of labour at term (PROBAAT trial): an open‐label, randomised controlled trial. Lancet. 2011;378:2095‐2103.
Diguisto C, Le Gouge A, Arthuis C, et al. Cervical ripening in prolonged pregnancies by silicone double balloon catheter versus vaginal dinoprostone slow release system: the MAGPOP randomised controlled trial. PLoS Med. 2021;18:e1003448.
Ten Eikelder ML, Neervoort F, Oude Rengerink K, et al. Induction of labour with a Foley catheter or oral misoprostol at term: the PROBAAT‐II study, a multicentre randomised controlled trial. BMC Pregnancy Childbirth. 2013;13:67.
Jozwiak M, ten Eikelder M, Oude Rengerink K, et al. Foley catheter versus vaginal misoprostol: randomized controlled trial (PROBAAT‐M study) and systematic review and meta‐analysis of literature. Am J Perinatol. 2014;31:145‐156.
ten Eikelder MLG, Mast K, van der Velden A, Bloemenkamp KWM, Mol BW. Induction of labor using a Foley catheter or misoprostol: a systematic review and meta‐analysis. Obstet Gynecol Surv. 2016;71:620‐630.
Mozurkewich EL, Chilimigras JL, Berman DR, et al. Methods of induction of labour: a systematic review. BMC Pregnancy Childbirth. 2011;11:84.
de Vaan MD, Ten Eikelder ML, Jozwiak M, et al. Mechanical methods for induction of labour. Cochrane Database Syst Rev. 2023;3:CD001233.
Edwards RK, Szychowski JM, Berger JL, et al. Foley catheter compared with the controlled‐release dinoprostone insert: a randomized controlled trial. Obstet Gynecol. 2014;123:1280‐1287.
Du C, Liu Y, Liu Y, Ding H, Zhang R, Tan J. Double‐balloon catheter vs. dinoprostone vaginal insert for induction of labor with an unfavorable cervix. Arch Gynecol Obstet. 2015;291:1221‐1227.
Grange J, Dimet J, Vital M, Le Thuaut A, Ducarme G. [Double‐balloon catheter compared to vaginal dinoprostone for cervical ripening in obese women at term]. Gynecol Obstet Fertil Senol. 2017;45:521‐527.
Lauterbach R, Ben Zvi D, Dabaja H, et al. Vaginal dinoprostone insert versus cervical ripening balloon for term induction of labor in obese nulliparas‐a randomized controlled trial. J Clin Med. 2022;11:2138.
Sarumi MA, Gherman RB, Bell TD, Jairath P, Johnson MJ, Burgess AL. A comparison of cervical ripening modalities among overweight and obese nulliparous gravidas. J Matern Fetal Neonatal Med. 2020;33:3804‐3808.
Estrade M, Diguisto C, Arnaud C, Ehlinger V, Vayssière C. Comparison of cesarean delivery rates after 3 methods of cervical ripening among obese women at or after 41 weeks – secondary analysis of two French randomized controlled trials: MAGPOP and CYTOPRO. Eur J Obstet Gynecol Reprod Biol. 2023;291:16‐21.
Croll DMR, De Vaan MDT, Moes SL, et al. Methods of induction of labor in women with obesity: a secondary analysis of two multicenter randomized controlled trials. Acta Obstet Gynecol Scand. 2024;103:470‐478. doi:10.1111/aogs.14737
Lim CC, Mahmood T. Obesity in pregnancy. Best Pract Res Clin Obstet Gynaecol. 2015;29:309‐319.
Vahratian A, Zhang J, Troendle JF, Savitz DA, Siega‐Ritz AM. Maternal prepregnancy overweight and obesity and the pattern of labor progression in term nulliparous women. Obstet Gynecol. 2004;104:943‐951.
Sebire NJ, Jolly M, Harris JP, et al. Maternal obesity and pregnancy outcome: a study of 287,213 pregnancies in London. Int J Obes Relat Metab Disord. 2001;25:1175‐1182.
Chu SY, Kim SY, Schmid CH, et al. Maternal obesity and risk of cesarean delivery: a meta‐analysis. Obes Rev. 2007;8:385‐394.
Zheng KF, Jones MN, Mol BW, Rolnik DL. The impact of body mass index on labour management and mode of delivery: a retrospective matched cohort study. Aust N Z J Obstet Gynaecol. 2023. Online ahead of print. doi:10.1111/ajo.13769
Wuntakal R, Kaler M, Hollingworth T. Women with high BMI: should they be managed differently due to antagonising action of leptin in labour? Med Hypotheses. 2013;80:767‐768.
Moynihan AT, Helir MP, Glavey SV, Smith TJ, Morrison JJ. Inhibitory effect of leptin on human uterine contractility in vitro. Am J Obstet Gynecol. 2006;195:504‐509.
Ducarme G, Martin S, Chesnoy V, Planche L, Berte MP, Netier‐Herault E. Prospective observational study investigating the effectiveness, safety, women's experiences and quality of life at 3 months regarding cervical ripening methods for induction of labor at term – the MATUCOL study protocol. PLoS One. 2022;17:e0262292.
Alsaif S, Mumtaz S, Wray S. A short review of adipokines, smooth muscle and uterine contractility. Life Sci. 2015;125:2‐8.
Soni S, Pappas K, Lesser ML, Blitz MJ, Augustine SA, Rochelson B. Is vaginal misoprostol more effective than oral misoprostol for cervical ripening in obese women? J Matern Fetal Neonatal Med. 2020;33:3476‐3483.
Helmig RB, Brogaard L, Hvidman L. Women's body mass index and oral administration of misoprostol for induction of labor – a retrospective cohort study. Obes Res Clin Pract. 2021;15:509‐511.