The course of borderline personality disorder from adolescence to early adulthood: A 5-year follow-up study.

Adolescence Borderline personality disorder Early intervention Follow-up Psychopathology

Journal

Comprehensive psychiatry
ISSN: 1532-8384
Titre abrégé: Compr Psychiatry
Pays: United States
ID NLM: 0372612

Informations de publication

Date de publication:
21 Mar 2024
Historique:
received: 05 12 2023
revised: 07 02 2024
accepted: 16 03 2024
medline: 25 3 2024
pubmed: 25 3 2024
entrez: 24 3 2024
Statut: aheadofprint

Résumé

Studies of the medium- to long-term clinical and functional course for treatment-seeking adolescents with borderline personality disorder (BPD) are lacking. This study aims to outline the psychopathological and functional status of participants, five years after being diagnosed with BPD during adolescence. Participants were originally enrolled in a randomized clinical trial that compared mentalization-based group treatment with treatment as usual for adolescents with BPD. Semi-structured interview assessments at five-year follow-up included the Schedules for Clinical Assessment in Neuropsychiatry and the Structured Clinical Interview for DSM-5 Personality Disorders. Attention deficit hyperactivity disorder (ADHD), alcohol, substance and tobacco use, posttraumatic stress disorder (PTSD), complex PTSD, and general functioning were assessed using self-report instruments. 97 of the original sample of 111 participants (87%) participated. They were aged 19-23 years. The most prevalent disorders were ADHD (59%), any personality disorder (47%) of which half continued to meet criteria for BPD (24%), anxiety disorders (37%), depressive disorders (32%), PTSD or complex PTSD (20%), schizophrenia (16%), and eating disorders (13%). Only 16% did not meet criteria for any mental disorder. Approximately half of the sample were in psychological and/or psychopharmacological treatment at the time of follow-up. Their general functioning remained impaired, with 36% not engaged in education, employment or training (NEET), which is nearly four times the rate of NEET in the same age group in the general population. Although stability of the categorical BPD diagnosis is modest, adolescents meeting diagnostic criteria for BPD show a broad range of poor outcomes at five-year follow-up. BPD appears to be a marker of general maladjustment during adolescence and a harbinger of severe problems during the transition to young adulthood. Early intervention programs for adolescents diagnosed with BPD should focus upon a broad range of functional and psychopathological outcomes, especially social and vocational support, rather than the narrow BPD diagnosis.

Sections du résumé

BACKGROUND BACKGROUND
Studies of the medium- to long-term clinical and functional course for treatment-seeking adolescents with borderline personality disorder (BPD) are lacking. This study aims to outline the psychopathological and functional status of participants, five years after being diagnosed with BPD during adolescence.
METHODS METHODS
Participants were originally enrolled in a randomized clinical trial that compared mentalization-based group treatment with treatment as usual for adolescents with BPD. Semi-structured interview assessments at five-year follow-up included the Schedules for Clinical Assessment in Neuropsychiatry and the Structured Clinical Interview for DSM-5 Personality Disorders. Attention deficit hyperactivity disorder (ADHD), alcohol, substance and tobacco use, posttraumatic stress disorder (PTSD), complex PTSD, and general functioning were assessed using self-report instruments.
RESULTS RESULTS
97 of the original sample of 111 participants (87%) participated. They were aged 19-23 years. The most prevalent disorders were ADHD (59%), any personality disorder (47%) of which half continued to meet criteria for BPD (24%), anxiety disorders (37%), depressive disorders (32%), PTSD or complex PTSD (20%), schizophrenia (16%), and eating disorders (13%). Only 16% did not meet criteria for any mental disorder. Approximately half of the sample were in psychological and/or psychopharmacological treatment at the time of follow-up. Their general functioning remained impaired, with 36% not engaged in education, employment or training (NEET), which is nearly four times the rate of NEET in the same age group in the general population.
CONCLUSIONS CONCLUSIONS
Although stability of the categorical BPD diagnosis is modest, adolescents meeting diagnostic criteria for BPD show a broad range of poor outcomes at five-year follow-up. BPD appears to be a marker of general maladjustment during adolescence and a harbinger of severe problems during the transition to young adulthood. Early intervention programs for adolescents diagnosed with BPD should focus upon a broad range of functional and psychopathological outcomes, especially social and vocational support, rather than the narrow BPD diagnosis.

Identifiants

pubmed: 38522259
pii: S0010-440X(24)00029-4
doi: 10.1016/j.comppsych.2024.152478
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

152478

Informations de copyright

Copyright © 2023. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of competing interest None.

Auteurs

Mie Sedoc Jørgensen (MS)

Psychiatric Research Unit, Mental Health Services, Region Zealand, 4200 Slagelse, Denmark. Electronic address: mipjo@regionsjaelland.dk.

Lise Møller (L)

Psychiatric Research Unit, Mental Health Services, Region Zealand, 4200 Slagelse, Denmark. Electronic address: lise.moeller.01@regionh.dk.

Sune Bo (S)

Psychiatric Research Unit, Mental Health Services, Region Zealand, 4200 Slagelse, Denmark; Department of Psychology, University of Copenhagen, Øster Farimagsgade 2A, 1353 Copenhagen, Denmark. Electronic address: sune.bo@rsyd.dk.

Mickey Kongerslev (M)

Mental Health Services, Region Zealand East, 4000 Roskilde, Denmark; Department of Psychology, University of Southern Denmark, Denmark. Electronic address: mkon@regionsjaelland.dk.

Lene Halling Hastrup (LH)

Psychiatric Research Unit, Mental Health Services, Region Zealand, 4200 Slagelse, Denmark; Danish Centre for Health Economics (DaCHE), University of Southern Denmark, Odense, Denmark. Electronic address: lhhs@regionsjaelland.dk.

Andrew Chanen (A)

Orygen, Melbourne, Australia, and Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia. Electronic address: andrew.chanen@orygen.org.au.

Ole Jakob Storebø (OJ)

Psychiatric Research Unit, Mental Health Services, Region Zealand, 4200 Slagelse, Denmark; Department of Psychology, University of Southern Denmark, Denmark. Electronic address: ojst@regionsjaelland.dk.

Stig Poulsen (S)

Department of Psychology, University of Copenhagen, Øster Farimagsgade 2A, 1353 Copenhagen, Denmark. Electronic address: stig.poulsen@psy.ku.dk.

Emma Beck (E)

Private Practice, Roskilde, Denmark.

Erik Simonsen (E)

Mental Health Services, Region Zealand East, 4000 Roskilde, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address: es@regionsjaelland.dk.

Classifications MeSH