Comparison of metabolic parameters between oral and total parenteral nutrition in children with severe eating disorders.
lipid metabolism
nutrition therapy
refeeding
severe eating disorders
total parenteral nutrition
Journal
Fukushima journal of medical science
ISSN: 2185-4610
Titre abrégé: Fukushima J Med Sci
Pays: Japan
ID NLM: 0374626
Informations de publication
Date de publication:
22 Mar 2024
22 Mar 2024
Historique:
medline:
25
3
2024
pubmed:
25
3
2024
entrez:
24
3
2024
Statut:
aheadofprint
Résumé
This study investigated changes of lipid parameters in children with severe eating disorders during refeeding in order to explore the optimal timing for lipid preparation administration. We prospectively assessed the physical conditions of patients with eating disorders after the start of nutrition therapy. The assessments were performed at admission and at 2 and 4 weeks. Lipid metabolism was assessed based on triglyceride (TG), total cholesterol (TC), and free carnitine (FC) levels, as well as acylcarnitine/free carnitine (AC/FC) ratio. A total of 18 patients were included. Of these, 12 and 6 received an oral diet (OD group) and total parenteral nutrition (TPN group), respectively. The mean body mass indexes at hospital admission were 12.8 kg/m Fat-free glucose-based nutrition promoted lipid metabolism over a 2-week period after the start of refeeding, suggesting that balanced energy and lipid intake are essential, even in TPN.
Sections du résumé
BACKGROUND
BACKGROUND
This study investigated changes of lipid parameters in children with severe eating disorders during refeeding in order to explore the optimal timing for lipid preparation administration.
METHODS
METHODS
We prospectively assessed the physical conditions of patients with eating disorders after the start of nutrition therapy. The assessments were performed at admission and at 2 and 4 weeks. Lipid metabolism was assessed based on triglyceride (TG), total cholesterol (TC), and free carnitine (FC) levels, as well as acylcarnitine/free carnitine (AC/FC) ratio.
RESULTS
RESULTS
A total of 18 patients were included. Of these, 12 and 6 received an oral diet (OD group) and total parenteral nutrition (TPN group), respectively. The mean body mass indexes at hospital admission were 12.8 kg/m
CONCLUSIONS
CONCLUSIONS
Fat-free glucose-based nutrition promoted lipid metabolism over a 2-week period after the start of refeeding, suggesting that balanced energy and lipid intake are essential, even in TPN.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM