Sensorineural correlates of failed functional recovery after natural regeneration of vestibular hair cells in adult mice.

VOR cFos hair cell mice regeneration vestibular

Journal

Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899

Informations de publication

Date de publication:
2024
Historique:
received: 16 10 2023
accepted: 23 02 2024
medline: 25 3 2024
pubmed: 25 3 2024
entrez: 25 3 2024
Statut: epublish

Résumé

Vestibular hair cells (HCs) are mechanoreceptors that sense head motions by modulating the firing rate of vestibular ganglion neurons (VGNs), whose central processes project to vestibular nucleus neurons (VNNs) and cerebellar neurons. We explored vestibular function after HC destruction in adult

Identifiants

DOI: 10.3389/fneur.2024.1322647 PMID: 38523617 PMC: PMC10960365
pubmed: 38523617
doi: 10.3389/fneur.2024.1322647
pmc: PMC10960365
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1322647

Informations de copyright

Copyright © 2024 Jáuregui, Scheinman, Bibriesca Mejia, Pruett, Zaini, Finkbeiner, Phillips, Gantz, Nguyen, Phillips and Stone.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Emmanuel J Jáuregui (EJ)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

Kelli L Scheinman (KL)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

Ingrid K Bibriesca Mejia (IK)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

Lindsay Pruett (L)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

Hannah Zaini (H)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

Connor Finkbeiner (C)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

Jonathan A Phillips (JA)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

Jay A Gantz (JA)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

Tot Bui Nguyen (TB)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

James O Phillips (JO)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

Jennifer S Stone (JS)

Department of Otolaryngology-Head and Neck Surgery and the Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, United States.

Classifications MeSH