Arachidonic acid metabolism as a therapeutic target in AKI-to-CKD transition.

acute kidney injury arachidonic acid chronic kidney disease inflammation oxidative stress renal cell carcinoma

Journal

Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923

Informations de publication

Date de publication:
2024
Historique:
received: 05 01 2024
accepted: 06 02 2024
medline: 25 3 2024
pubmed: 25 3 2024
entrez: 25 3 2024
Statut: epublish

Résumé

Arachidonic acid (AA) is a main component of cell membrane lipids. AA is mainly metabolized by three enzymes: cyclooxygenase (COX), lipoxygenase (LOX) and cytochrome P450 (CYP450). Esterified AA is hydrolysed by phospholipase A

Identifiants

pubmed: 38523633
doi: 10.3389/fphar.2024.1365802
pii: 1365802
pmc: PMC10957658
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1365802

Informations de copyright

Copyright © 2024 Li, Suo, Wang, Zou, Nie, Zhao and Miao.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Xiao-Jun Li (XJ)

School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Department of Nephrology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.

Ping Suo (P)

School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Yan-Ni Wang (YN)

School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Liang Zou (L)

School of Food and Bioengineering, Chengdu University, Chengdu, Sichuan, China.

Xiao-Li Nie (XL)

Department of Nephrology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.

Ying-Yong Zhao (YY)

School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Hua Miao (H)

School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Classifications MeSH