HIV Interacts with Posttraumatic Stress Disorder to Impact Fear Psychophysiology in Trauma-Exposed Black Women.

HIV PTSD childhood trauma women

Journal

Women's health reports (New Rochelle, N.Y.)
ISSN: 2688-4844
Titre abrégé: Womens Health Rep (New Rochelle)
Pays: United States
ID NLM: 101768931

Informations de publication

Date de publication:
2024
Historique:
accepted: 31 01 2024
medline: 25 3 2024
pubmed: 25 3 2024
entrez: 25 3 2024
Statut: epublish

Résumé

The prevalence of posttraumatic stress disorder (PTSD) among people living with HIV (PLWH) is higher than in the general population and can impact health behaviors. The influence of HIV on PTSD psychophysiology requires further investigation due to implications for the treatment of PTSD in PLWH. Utilizing fear-potentiated startle (FPS), we aimed to interrogate the influence of PTSD and HIV on fear responses. Women (18-65 years of age) recruited from the Women's Interagency HIV Study in Atlanta, GA ( Women with PTSD, who did not have HIV, exhibited a greater startle response compared to women without PTSD or HIV during late acquisition to both the danger cue, reinforced conditioned stimulus (CS+, Our findings indicate that HIV further modifies fear psychophysiology in WLH with comorbid PTSD, highlighting the importance of considering HIV status in conjunction with PTSD treatment.

Sections du résumé

Background UNASSIGNED
The prevalence of posttraumatic stress disorder (PTSD) among people living with HIV (PLWH) is higher than in the general population and can impact health behaviors. The influence of HIV on PTSD psychophysiology requires further investigation due to implications for the treatment of PTSD in PLWH.
Objective UNASSIGNED
Utilizing fear-potentiated startle (FPS), we aimed to interrogate the influence of PTSD and HIV on fear responses.
Materials and Methods UNASSIGNED
Women (18-65 years of age) recruited from the Women's Interagency HIV Study in Atlanta, GA (
Results UNASSIGNED
Women with PTSD, who did not have HIV, exhibited a greater startle response compared to women without PTSD or HIV during late acquisition to both the danger cue, reinforced conditioned stimulus (CS+,
Conclusion UNASSIGNED
Our findings indicate that HIV further modifies fear psychophysiology in WLH with comorbid PTSD, highlighting the importance of considering HIV status in conjunction with PTSD treatment.

Identifiants

pubmed: 38523844
doi: 10.1089/whr.2023.0133
pii: 10.1089/whr.2023.0133
pmc: PMC10960165
doi:

Types de publication

Journal Article

Langues

eng

Pagination

231-241

Informations de copyright

© Susie Turkson et al., 2024; Published by Mary Ann Liebert, Inc.

Déclaration de conflit d'intérêts

No competing financial interests exist.

Auteurs

Susie Turkson (S)

Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia, USA.

Sanne J H van Rooij (SJH)

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.

Abigail Powers (A)

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.

Ighovwerha Ofotokun (I)

Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Grady Health System, Atlanta, Georgia, USA.

Seth D Norrholm (SD)

Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan, USA.

Gretchen N Neigh (G)

Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia, USA.

Tanja Jovanovic (T)

Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan, USA.

Vasiliki Michopoulos (V)

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.
Emory National Primate Research Center, Atlanta, Georgia, USA.

Classifications MeSH