Association of
COVID-19
Inflammatory parameters
Outcome
PADI2
PADI4
Polymorphisms
Journal
Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560
Informations de publication
Date de publication:
30 Mar 2024
30 Mar 2024
Historique:
received:
15
11
2023
revised:
27
02
2024
accepted:
10
03
2024
medline:
25
3
2024
pubmed:
25
3
2024
entrez:
25
3
2024
Statut:
epublish
Résumé
Enzymes of the peptidylarginine deiminase family (PADs) play a relevant role in the pathogenesis of COVID-19. However, the association of single nucleotide polymorphisms (SNPs) in their genes with COVID-19 severity and death is unknown. We included 1045 patients who were diagnosed with COVID-19 between October 2020 and December 2021. All subjects were genotyped for 291 patients presented had severe COVID-19 according to PaO Our results suggest that the haplotypic combination of GTACC and some individual genotypes of
Sections du résumé
Background
UNASSIGNED
Enzymes of the peptidylarginine deiminase family (PADs) play a relevant role in the pathogenesis of COVID-19. However, the association of single nucleotide polymorphisms (SNPs) in their genes with COVID-19 severity and death is unknown.
Methodology
UNASSIGNED
We included 1045 patients who were diagnosed with COVID-19 between October 2020 and December 2021. All subjects were genotyped for
Results
UNASSIGNED
291 patients presented had severe COVID-19 according to PaO
Conclusions
UNASSIGNED
Our results suggest that the haplotypic combination of GTACC and some individual genotypes of
Identifiants
pubmed: 38524554
doi: 10.1016/j.heliyon.2024.e27997
pii: S2405-8440(24)04028-3
pmc: PMC10958703
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e27997Informations de copyright
© 2024 The Authors. Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.