Metabolic Syndrome and Heart Transplantation: An Underestimated Risk Factor?
cardiac allograft vasculopathy
heart transplantation
long-term mortality
long-term outcome
metabolic syndrome
Journal
Transplant international : official journal of the European Society for Organ Transplantation
ISSN: 1432-2277
Titre abrégé: Transpl Int
Pays: Switzerland
ID NLM: 8908516
Informations de publication
Date de publication:
2024
2024
Historique:
received:
24
11
2022
accepted:
02
01
2024
medline:
25
3
2024
pubmed:
25
3
2024
entrez:
25
3
2024
Statut:
epublish
Résumé
Metabolic Syndrome (MetS), a multifactorial condition that increases the risk of cardio-vascular events, is frequent in Heart-transplant (HTx) candidates and worsens with immunosuppressive therapy. The aim of the study was to analyze the impact of MetS on long-term outcome of HTx patients. Since 2007, 349 HTx patients were enrolled. MetS was diagnosed if patients met revised NCEP-ATP III criteria before HTx, at 1, 5 and 10 years of follow-up. MetS was present in 35% of patients pre-HTx and 47% at 1 year follow-up. Five-year survival in patients with both pre-HTx (65% vs. 78%,
Identifiants
pubmed: 38525207
doi: 10.3389/ti.2024.11075
pii: 11075
pmc: PMC10959251
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
11075Informations de copyright
Copyright © 2024 Sponga, Vendramin, Ferrara, Marinoni, Valdi, Di Nora, Nalli, Benedetti, Piani, Lechiancole, Parpinel, Bortolotti and Livi.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.