Distal Pancreatectomy for Body Pancreatic Ductal Adenocarcinoma: Is Splenectomy Necessary? A Propensity Score Matched Study.
Body pancreatic ductal adenocarcinoma
Distal pancreatectomy
Spleen preservation
Splenectomy
Journal
Annals of surgical oncology
ISSN: 1534-4681
Titre abrégé: Ann Surg Oncol
Pays: United States
ID NLM: 9420840
Informations de publication
Date de publication:
25 Mar 2024
25 Mar 2024
Historique:
received:
11
01
2024
accepted:
10
03
2024
medline:
25
3
2024
pubmed:
25
3
2024
entrez:
25
3
2024
Statut:
aheadofprint
Résumé
The value of splenectomy for body localization (≥ 5 cm from spleen hilum) of pancreatic ductal adenocarcinoma (B-PDAC) is uncertain. This study assessed spleen-preserving distal pancreatectomy (SPDP) results for B-PDAC. This single-center study included patients who underwent SPDP (Warshaw's technique) or distal splenopancreactomy (DSP) for B-PDAC from 2008 to 2019. Propensity score matching was performed to balance SPDP and DSP patients regarding sex, age, American Society of Anesthesiologists (ASA), body mass index (BMI), laparoscopy, pathological features [American Joint Committee on Cancer (AJCC)/tumor node metastasis classification (TNM)], margins, and neoadjuvant/adjuvant therapies. A total of 129 patients (64 male, median age 68 years, median BMI 24 kg/m SPDP for B-PDAC is associated with less postoperative morbidity than DSP, without impairing oncological outcomes.
Sections du résumé
BACKGROUND
BACKGROUND
The value of splenectomy for body localization (≥ 5 cm from spleen hilum) of pancreatic ductal adenocarcinoma (B-PDAC) is uncertain. This study assessed spleen-preserving distal pancreatectomy (SPDP) results for B-PDAC.
PATIENTS AND METHODS
METHODS
This single-center study included patients who underwent SPDP (Warshaw's technique) or distal splenopancreactomy (DSP) for B-PDAC from 2008 to 2019. Propensity score matching was performed to balance SPDP and DSP patients regarding sex, age, American Society of Anesthesiologists (ASA), body mass index (BMI), laparoscopy, pathological features [American Joint Committee on Cancer (AJCC)/tumor node metastasis classification (TNM)], margins, and neoadjuvant/adjuvant therapies.
RESULTS
RESULTS
A total of 129 patients (64 male, median age 68 years, median BMI 24 kg/m
CONCLUSION
CONCLUSIONS
SPDP for B-PDAC is associated with less postoperative morbidity than DSP, without impairing oncological outcomes.
Identifiants
pubmed: 38526834
doi: 10.1245/s10434-024-15220-0
pii: 10.1245/s10434-024-15220-0
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. Society of Surgical Oncology.
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