Heterologous Biosynthesis of Kauralexin A1 in

Saccharomyces cerevisiae Zea mays diterpene phytoalexins ent-kaurene kauralexin A1 metabolic engineering

Journal

Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755

Informations de publication

Date de publication:
26 Mar 2024
Historique:
medline: 26 3 2024
pubmed: 26 3 2024
entrez: 26 3 2024
Statut: aheadofprint

Résumé

Kauralexin A1 (KA1) is a key intermediate of the kauralexin A series metabolites of maize phytoalexins. However, their application is severely limited by their low abundance in maize. In this study, an efficient biosynthetic pathway was constructed to produce KA1 in

Identifiants

DOI: 10.1021/acs.jafc.4c00856 PMID: 38529564
pubmed: 38529564
doi: 10.1021/acs.jafc.4c00856
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Ruiqi Chen (R)

Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
Zhejiang Institute of Tianjin University (Shaoxing), Shaoxing 312300, China.

Jingru Wang (J)

Zhejiang Institute of Tianjin University (Shaoxing), Shaoxing 312300, China.
School of life science, Liaoning University, Shenyang 110036, China.

Junsong Xu (J)

Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
Zhejiang Institute of Tianjin University (Shaoxing), Shaoxing 312300, China.

Shengxin Nie (S)

Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
Zhejiang Institute of Tianjin University (Shaoxing), Shaoxing 312300, China.
ORCID: 0009-0009-4893-4332

Chen Chen (C)

Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
Zhejiang Institute of Tianjin University (Shaoxing), Shaoxing 312300, China.

Yukun Li (Y)

Zhejiang Institute of Tianjin University (Shaoxing), Shaoxing 312300, China.

Yanni Li (Y)

Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.

Jianwei He (J)

School of life science, Liaoning University, Shenyang 110036, China.

Weiguo Li (W)

Zhejiang Institute of Tianjin University (Shaoxing), Shaoxing 312300, China.

Mingzhang Wen (M)

Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.

Jianjun Qiao (J)

Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
Zhejiang Institute of Tianjin University (Shaoxing), Shaoxing 312300, China.
ORCID: 0000-0002-8126-2074

Classifications MeSH