Pulmonary Adverse Events in Cancer Immunotherapy: Case Studies of CT Patterns.
hypersensitivity pneumonitis
immune-checkpoint inhibitors
immune-related adverse events
lung toxicity
non-specific interstitial pneumonia
organizing pneumonia
sarcoid-like reaction
Journal
Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402
Informations de publication
Date de publication:
14 Mar 2024
14 Mar 2024
Historique:
received:
15
02
2024
revised:
06
03
2024
accepted:
12
03
2024
medline:
27
3
2024
pubmed:
27
3
2024
entrez:
27
3
2024
Statut:
epublish
Résumé
Immune-checkpoint inhibitors have profoundly changed cancer treatment, improving the prognosis of many oncologic patients. However, despite the good efficacy of these drugs, their mechanism of action, which involves the activation of the immune system, can lead to immune-related adverse events, which may affect almost all organs. Pulmonary adverse events are relatively common, and potentially life-threatening complications may occur. The diagnosis is challenging due to the wide and non-specific spectrum of clinical and radiological manifestations. The role of the radiologist is to recognize and diagnose pulmonary immune-related adverse events, possibly even in the early stages, to estimate their extent and guide patients' management.
Identifiants
pubmed: 38535033
pii: diagnostics14060613
doi: 10.3390/diagnostics14060613
pii:
doi:
Types de publication
Journal Article
Langues
eng