Vacuum-assisted mini-percutaneous nephrolithotomy is associated with lower rates of infectious complications compared to vacuum-cleaner procedure in patients at high risk for infections: a single-center experience.

Aspiration Infectious complications Percutaneous nephrolithotomy Safety Stone

Journal

World journal of urology
ISSN: 1433-8726
Titre abrégé: World J Urol
Pays: Germany
ID NLM: 8307716

Informations de publication

Date de publication:
27 Mar 2024
Historique:
received: 19 09 2023
accepted: 21 02 2024
medline: 27 3 2024
pubmed: 27 3 2024
entrez: 27 3 2024
Statut: epublish

Résumé

To evaluate the impact of vacuum-assisted mini-percutaneous nephrolithotomy (vamPCNL) vs. vacuum-cleaner mPCNL (vcmPCNL) on the rate of postoperative infectious complications in a cohort of patients with high risk factors for infections. We retrospectively analysed data from 145 patients who underwent mPCNL between 01/2016 and 12/2022. Patient's demographics, stones characteristics and operative data were collected. vamPCNL and vcmPCNL were performed based on the surgeon's preference. High-risk patients were defied as having ≥ 2 predisposing factors for infections such as a history of previous urinary tract infections, positive urine culture before surgery, stone diameter ≥ 3 cm, diabetes mellitus and hydronephrosis. Complications were graded according to modified Clavien classification. Descriptive statistics and logistic regression models were used to identify factors associated with postoperative infectious complications. vamPCNL and vcmPCNL were performed in 94 (64.8%) and 51 (35.2%) cases, respectively. After surgery, infectious complications occurred in 43 (29.7%) participants. Patients who developed infectious complications had larger stone volume (p = 0.02) and higher rate of multiple stones (p = 0.01) than those who did not. Infectious complications occurred more frequently after vcmPCNL than vamPCNL (55.9% vs. 44.1%. p = 0.01) in high-risk patients. Longer operative time (p < 0.01) and length of stay (p < 0.01) were observed in cases with infectious complications. At multivariable logistic regression analysis, longer operative time (OR 1.1, p = 0.02) and vcmPCNL (OR 3.1, p = 0.03) procedures were independently associated with the risk of infectious complications post mPCNL, after accounting for stone volume. One out of three high-risk patients showed infectious complications after mPCNL. vamPCL and shorter operative time were independent protective factors for infections after surgery.

Identifiants

pubmed: 38536503
doi: 10.1007/s00345-024-04897-3
pii: 10.1007/s00345-024-04897-3
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

200

Informations de copyright

© 2024. The Author(s).

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Auteurs

Andrea Marmiroli (A)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.

Marco Nizzardo (M)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.

Stefano Paolo Zanetti (SP)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.

Gianpaolo Lucignani (G)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.

Matteo Turetti (M)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.

Carlo Silvani (C)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.

Franco Gadda (F)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.

Fabrizio Longo (F)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.

Elisa De Lorenzis (E)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.

Giancarlo Albo (G)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy. albo.giancarlo@gmail.com.
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. albo.giancarlo@gmail.com.

Andrea Salonia (A)

Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, University Vita-Salute San Raffaele, Milan, Italy.

Emanuele Montanari (E)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

Luca Boeri (L)

Department of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.

Classifications MeSH