Glomerular Filtration Rate Estimation Using β
cancer patients
estimating equations
β(2-)microglobulin (B2M)
β-trace-protein (BTP) glomerular filtration rate (GFR)
Journal
American journal of kidney diseases : the official journal of the National Kidney Foundation
ISSN: 1523-6838
Titre abrégé: Am J Kidney Dis
Pays: United States
ID NLM: 8110075
Informations de publication
Date de publication:
25 Mar 2024
25 Mar 2024
Historique:
received:
10
08
2023
revised:
06
12
2023
accepted:
02
01
2024
medline:
28
3
2024
pubmed:
28
3
2024
entrez:
27
3
2024
Statut:
aheadofprint
Résumé
β Cross-sectional analysis. Prospective cohort of 1,200 patients with active solid tumors recruited between April 2015 and September 2017. CKD-EPI equations without race combining B2M and/or BTP with creatinine with or without cystatin C (2-, 3- or 4-marker panel eGFR). Performance of equations compared to eGFR Bias was defined as the median of the differences between mGFR and eGFR. 1-P Mean (SD) age and mGFR were 58.8 (13.2) years and 78.4 (21.7) ml/min/1.73 m Participants may have had better clinical performance status than the general population of patients with solid tumors. B2M and BTP can improve the accuracy of eGFR and may be useful as confirmatory tests in patients with solid tumors, either by inclusion in multi-marker panel equation with creatinine and cystatin C, or by substituting for cystatin C in combination with creatinine.
Identifiants
pubmed: 38537905
pii: S0272-6386(24)00684-X
doi: 10.1053/j.ajkd.2024.01.532
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024. Published by Elsevier Inc.