Encoding manual dexterity through modulation of intrinsic alpha band connectivity.

The human hand possesses both consolidated motor skills and remarkable flexibility in adapting to ongoing task demands. However, the underlying mechanisms by which the brain balances stability and flexibility remain unknown. In the absence of external input or behavior, spontaneous (intrinsic) brain connectivity is thought to represent a prior of stored memories. In this study, we investigated how manual dexterity modulates spontaneous functional connectivity in the motor cortex during hand movement. Using magnetoencephalography (MEG), in 47 human participants (both sexes) we examined connectivity modulations in the alpha and beta frequency bands at rest and during two motor tasks (

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