A systematic review: is Anopheles vagus a species complex?

Anopheles limosus Anopheles vagus Anopheles vagus limosus Phylogeny Sibling species Species complex

Journal

Malaria journal
ISSN: 1475-2875
Titre abrégé: Malar J
Pays: England
ID NLM: 101139802

Informations de publication

Date de publication:
27 Mar 2024
Historique:
received: 07 03 2023
accepted: 21 02 2024
medline: 28 3 2024
pubmed: 28 3 2024
entrez: 28 3 2024
Statut: epublish

Résumé

Anopheles vagus (subgenus Cellia) has been identified as a vector for malaria, filariasis, and Japanese encephalitis in Asia. Sporozoites of Plasmodium falciparum and Plasmodium vivax have been found in this zoophilic mosquito in Asia and Indonesia. This study systematically reviews publications regarding An. vagus species, variation, bio-ecology, and malaria transmission in various localities in Asia, especially Indonesia, to determine whether the current data support An. vagus as a species complex. The databases Pubmed, Scopus, Europe PMC, and Proquest were searched to identify information regarding the morphology, karyotypes, polytene chromosome, cross-mating, ecology, and molecular identification of An. vagus was then evaluated to determine whether there were possible species complexes. Of the 1326 articles identified, 15 studies were considered for synthesis. The Anopheles spp. samples for this study came from Asia. Eleven studies used morphology to identify An. vagus, with singular studies using each of karyotype identification, chromosomal polytene identification, and cross-breeding experiments. Ten studies used molecular techniques to identify Anopheles spp., including An. vagus. Most studies discovered morphological variations of An. vagus either in the same or different areas and ecological settings. In this review, the members of An. vagus sensu lato grouped based on morphology (An. vagus, An. vagus vagus, An. vagus limosus, and An. limosus), karyotyping (form A and B), and molecular (An. vagus genotype A and B, An. vagus AN4 and AN5). Genetic analysis revealed a high conservation of the ITS2 fragment among members except for the An. vagus genotype B, which was, in fact, Anopheles sundaicus. This review also identified that An. vagus limosus and An. vagus vagus were nearly identical to the ITS2 sequence. Literature review studies revealed that An. vagus is conspecific despite the distinct morphological characteristic of An. vagus and An. limosus. Further information using another barcoding tool, such as mitochondrial COI and ND6 and experimental cross-mating between the An. vagus and An. limosus may provide additional evidence for the status of An. vagus as a species complex.

Sections du résumé

BACKGROUND BACKGROUND
Anopheles vagus (subgenus Cellia) has been identified as a vector for malaria, filariasis, and Japanese encephalitis in Asia. Sporozoites of Plasmodium falciparum and Plasmodium vivax have been found in this zoophilic mosquito in Asia and Indonesia. This study systematically reviews publications regarding An. vagus species, variation, bio-ecology, and malaria transmission in various localities in Asia, especially Indonesia, to determine whether the current data support An. vagus as a species complex.
METHODS METHODS
The databases Pubmed, Scopus, Europe PMC, and Proquest were searched to identify information regarding the morphology, karyotypes, polytene chromosome, cross-mating, ecology, and molecular identification of An. vagus was then evaluated to determine whether there were possible species complexes.
RESULTS RESULTS
Of the 1326 articles identified, 15 studies were considered for synthesis. The Anopheles spp. samples for this study came from Asia. Eleven studies used morphology to identify An. vagus, with singular studies using each of karyotype identification, chromosomal polytene identification, and cross-breeding experiments. Ten studies used molecular techniques to identify Anopheles spp., including An. vagus. Most studies discovered morphological variations of An. vagus either in the same or different areas and ecological settings. In this review, the members of An. vagus sensu lato grouped based on morphology (An. vagus, An. vagus vagus, An. vagus limosus, and An. limosus), karyotyping (form A and B), and molecular (An. vagus genotype A and B, An. vagus AN4 and AN5). Genetic analysis revealed a high conservation of the ITS2 fragment among members except for the An. vagus genotype B, which was, in fact, Anopheles sundaicus. This review also identified that An. vagus limosus and An. vagus vagus were nearly identical to the ITS2 sequence.
CONCLUSION CONCLUSIONS
Literature review studies revealed that An. vagus is conspecific despite the distinct morphological characteristic of An. vagus and An. limosus. Further information using another barcoding tool, such as mitochondrial COI and ND6 and experimental cross-mating between the An. vagus and An. limosus may provide additional evidence for the status of An. vagus as a species complex.

Identifiants

pubmed: 38539155
doi: 10.1186/s12936-024-04888-0
pii: 10.1186/s12936-024-04888-0
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

88

Informations de copyright

© 2024. The Author(s).

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Auteurs

Dalilah Dalilah (D)

Science and Biomedical Doctoral Programme, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.
Department of Parasitology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.

Din Syafruddin (D)

Department of Parasitology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Hasanuddin University Medical Research Center (HUMRC), Makassar, Indonesia.

Irsan Saleh (I)

Department of Pharmacology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.

Ahmad Ghiffari (A)

Department of Parasitology, Faculty of Medicine, Universitas Muhammadiyah Palembang, Palembang, Indonesia.

Leo Vernadesly (L)

Medical Student, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.

Lepa Syahrani (L)

Doctoral Program, Department of Biology, Faculty of Mathematics and Natural Science, University of Indonesia, Depok, Indonesia.
Eijkman Research Center for Molecular Biology, National Research and Innovation Agency (BRIN), Cibinong, Indonesia.

Irdayanti Irdayanti (I)

Hasanuddin University Medical Research Center (HUMRC), Makassar, Indonesia.

Chairil Anwar (C)

Department of Parasitology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia. chairil53@fk.unsri.ac.id.

Classifications MeSH