Radiotherapy for Metastatic Epidural Spinal Cord Compression with Increased Doses: Final Results of the RAMSES-01 Trial.

highly conformal radiotherapy historical control group increased doses local progression-free survival metastatic epidural spinal cord compression phase 2 trial

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
14 Mar 2024
Historique:
received: 26 02 2024
revised: 07 03 2024
accepted: 11 03 2024
medline: 28 3 2024
pubmed: 28 3 2024
entrez: 28 3 2024
Statut: epublish

Résumé

Patients with metastatic epidural spinal cord compression (MESCC) and favorable survival prognoses may benefit from radiation doses exceeding 10 × 3.0 Gy. In a multi-center phase 2 trial, patients receiving 15 × 2.633 Gy (41.6 Gy

Identifiants

pubmed: 38539484
pii: cancers16061149
doi: 10.3390/cancers16061149
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : European Development Fund through the Interreg Deutschland-Danmark program
ID : 094 -1.1-18

Auteurs

Dirk Rades (D)

Department of Radiation Oncology, University of Lubeck, 23562 Lubeck, Germany.

Darejan Lomidze (D)

Radiation Oncology Department, Tbilisi State Medical University, 0186 Tbilisi, Georgia.
Ingorokva High Medical Technology University Clinic, 0144 Tbilisi, Georgia.

Natalia Jankarashvili (N)

Department of Radiation Oncology, Acad. F. Todua Medical Center-Research Institute of Clinical Medicine, 0112 Tbilisi, Georgia.

Fernando Lopez Campos (F)

Department of Radiation Oncology, University Hospital Ramón y Cajal, 28034 Madrid, Spain.

Arturo Navarro-Martin (A)

Department of Radiation Oncology, Instituto Catalán de Oncología, 08908 l'Hospitalet de Llobregat, Spain.

Barbara Segedin (B)

Department of Radiotherapy, Institute of Oncology Ljubljana and Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.

Blaz Groselj (B)

Department of Radiotherapy, Institute of Oncology Ljubljana and Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.

Christian Staackmann (C)

Department of Radiation Oncology, University of Lubeck, 23562 Lubeck, Germany.

Charlotte Kristiansen (C)

Department of Oncology, Vejle Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.

Kristopher Dennis (K)

Division of Radiation Oncology, The Ottawa Hospital and the University of Ottawa, Ottawa, ON K1Y 4E9, Canada.

Steven E Schild (SE)

Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ 85054, USA.

Jon Cacicedo (J)

Department of Radiation Oncology, Cruces University Hospital/Biobizkaia Health Research Institute, 48903 Barakaldo, Spain.

Classifications MeSH