Real-World Outcome of Treatment with Single-Agent Ibrutinib in Italian Patients with Chronic Lymphocytic Leukemia: Final Results of the EVIdeNCE Study.

chronic lymphocytic leukemia clinical outcomes effectiveness ibrutinib real-world evidence retention

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
20 Mar 2024
Historique:
received: 21 01 2024
revised: 07 03 2024
accepted: 15 03 2024
medline: 28 3 2024
pubmed: 28 3 2024
entrez: 28 3 2024
Statut: epublish

Résumé

Real-world data in clinical practice are needed to confirm the efficacy and safety that ibrutinib has demonstrated in clinical trials of patients with chronic lymphocytic leukemia (CLL). We described the real-world persistence rate, patterns of use, and clinical outcomes in 309 patients with CLL receiving single-agent ibrutinib in first line (1L,

Identifiants

DOI: 10.3390/cancers16061228 PMID: 38539561
pubmed: 38539561
pii: cancers16061228
doi: 10.3390/cancers16061228
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Johnson & Johnson
ID : N/A

Auteurs

Francesca Romana Mauro (FR)

Ematologia, Sapienza Università di Roma, 00185 Roma, Italy.
ORCID: 0000-0003-2425-9474

Potito Rosario Scalzulli (PR)

Ospedale "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.

Lydia Scarfò (L)

Università Vita-Salute San Raffaele, 20132 Milano, Italy.
IRCCS Ospedale San Raffaele, 20132 Milano, Italy.

Carla Minoia (C)

Hematology Unit, IRCCS Istituto Tumori "Giovanni Paolo II", 70124 Bari, Italy.

Roberta Murru (R)

Hematology and Stem Cell Transplantation Unit, Ospedale Oncologico A. Businco, ARNAS G. Brotzu, 09134 Cagliari, Italy.
ORCID: 0000-0001-9792-9542

Paolo Sportoletti (P)

Sezione di Ematologia, Università degli Studi di Perugia, 06123 Perugia, Italy.
ORCID: 0000-0002-5630-9862

Ferdinando Frigeri (F)

AORN "Sant'Anna e San Sebastiano", 81100 Caserta, Italy.

Francesco Albano (F)

Hematology and Stem Cell Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70121 Bari, Italy.
ORCID: 0000-0001-7926-6052

Nicola Di Renzo (N)

UOC Ematologia e Trapianto di Cellule Staminali-PO "Vito Fazzi" ASL Lecce, 73100 Lecce, Italy.

Alessandro Sanna (A)

AOU Careggi, 50121 Firenze, Italy.

Luca Laurenti (L)

Policlinico A. Gemelli, 00168 Roma, Italy.
ORCID: 0000-0002-8327-1396

Massimo Massaia (M)

SC Ematologia-AO S. Croce e Carle, 12100 Cuneo, Italy.
Dipartimento di Biotecnologie Molecolari e Scienze per la Salute, Università degli Studi di Torino, 10124 Torino, Italy.

Ramona Cassin (R)

Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico of Milan, 20122 Milano, Italy.

Marta Coscia (M)

Dipartimento di Biotecnologie Molecolari e Scienze per la Salute, Università degli Studi di Torino, 10124 Torino, Italy.
SC Ematologia U, AOU Città della Salute e della Scienza di Torino, 10126 Torino, Italy.
ORCID: 0000-0003-2123-7675

Caterina Patti (C)

UOC Oncoematologia, Ospedali Riuniti Villa Sofia-Cervello, 90146 Palermo, Italy.

Elsa Pennese (E)

UOC Ematologia Clinica, ASL Pescara, 65124 Pescara, Italy.

Agostino Tafuri (A)

Ematologia, AOU Sant'Andrea, Sapienza Università di Roma, 00185 Roma, Italy.

Annalisa Chiarenza (A)

UOC Ematologia, AOU Policlinico G.Rodolico-San Marco, 95123 Catania, Italy.

Piero Galieni (P)

UOC Ematologia e Terapia Cellulare, Ospedale Mazzoni, 63100 Ascoli Piceno, Italy.

Omar Perbellini (O)

UOC Ematologia, Azienda ULSS 8 Berica, 36100 Vicenza, Italy.

Carmine Selleri (C)

Hematology and Bone Marrow Transplant Center, Department of Medicine and Surgery, University of Salerno, 84081 Salerno, Italy.
ORCID: 0000-0002-5861-8984

Catello Califano (C)

UOC Ematologia, PO Andrea Tortora-Pagani, 84016 Pagani, Italy.

Felicetto Ferrara (F)

AORN Antonio Cardarelli, 80131 Napoli, Italy.

Antonio Cuneo (A)

Department of Medical Science, Università degli Studi di Ferrara, 44121 Ferrara, Italy.
ORCID: 0000-0003-2001-1308

Marco Murineddu (M)

Ematologia, Ospedale San Francesco ASL Nuoro, 08100 Nuoro, Italy.

Gaetano Palumbo (G)

SC Ematologia, AOU Policlinico Foggia, 71122 Foggia, Italy.

Ilaria Scortechini (I)

Azienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.

Alessandra Tedeschi (A)

Divisione di Ematologia, ASST GOM Niguarda, 20162 Milano, Italy.

Livio Trentin (L)

Dipartimento di Medicina, UOC Ematologia, Università di Padova, 35122 Padova, Italy.
ORCID: 0000-0003-1222-6149

Marzia Varettoni (M)

Divisione di Ematologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
ORCID: 0000-0001-7304-1629

Fabrizio Pane (F)

Division of Hematology, Department of Clinical Medicine and Surgery, Università di Napoli Federico II, 80131 Napoli, Italy.
ORCID: 0000-0003-2563-4125

Anna Marina Liberati (AM)

AO Santa Maria, Università degli Studi Di Perugia, 05100 Terni, Italy.
ORCID: 0000-0002-3686-3188

Francesco Merli (F)

Ematologia AUSL-IRCCS Reggio Emilia, 42123 Reggio Emilia, Italy.

Lucia Morello (L)

IRCCS Humanitas Research Hospital-Humanitas Cancer Center, 20089 Rozzano, Italy.

Gerardo Musuraca (G)

IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
ORCID: 0000-0003-1947-1032

Monica Tani (M)

Haematology Unit, Ospedale S. Maria delle Croci, 48121 Ravenna, Italy.

Adalberto Ibatici (A)

IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.

Giulia Regazzoni (G)

Johnson & Johnson Innovative Medicine, 20126 Milano, Italy.

Michele Di Candia (M)

Johnson & Johnson Innovative Medicine, 20126 Milano, Italy.

Maria Palma (M)

Johnson & Johnson Innovative Medicine, 20126 Milano, Italy.

Danilo Arienti (D)

Johnson & Johnson Innovative Medicine, 20126 Milano, Italy.

Stefano Molica (S)

Dipartimento Onco-Ematologico, Azienda Ospedaliera Pugliese-Ciaccio, 88100 Catanzaro, Italy.
Queens Centre for Oncology and Haematology, Castle Hill Hospital, Hull University NHS Trust, Hull HU16 5JQ, UK.
ORCID: 0000-0003-2795-6507

Classifications MeSH