Association of Plasma Brain-Derived Tau With Functional Outcome After Ischemic Stroke.

Journal

Neurology
ISSN: 1526-632X
Titre abrégé: Neurology
Pays: United States
ID NLM: 0401060

Informations de publication

Date de publication:
27 Feb 2024
Historique:
medline: 28 3 2024
pubmed: 28 3 2024
entrez: 28 3 2024
Statut: ppublish

Résumé

To investigate whether circulating acute-phase brain-derived tau (BD-tau) is associated with functional outcome after ischemic stroke. Plasma tau was measured by a novel assay that selectively quantifies BD-tau in the This study included 454 and 364 cases from the BD-tau is a promising blood-based biomarker of ischemic stroke outcomes, and future studies in larger cohorts are warranted.

Identifiants

DOI: 10.1212/WNL.0000000000209129 PMID: 38545929
pubmed: 38545929
doi: 10.1212/WNL.0000000000209129
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e209129

Auteurs

Tara M Stanne (TM)

From the Department of Laboratory Medicine (T.M.S., C.B., C.J.), Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg; Department of Clinical Genetics and Genomics (T.M.S., C.J.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Psychiatry and Neurochemistry (F.G.-O., T.K., K.B.), Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg; Clinical Neurochemistry Laboratory (F.G.-O., K.B.); Department of Research, Development, Education and Innovation (C.B.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg; Department of Neurology (K.J.), Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; and Department of Psychiatry (T.K.), University of Pittsburgh.

Fernando Gonzalez-Ortiz (F)

From the Department of Laboratory Medicine (T.M.S., C.B., C.J.), Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg; Department of Clinical Genetics and Genomics (T.M.S., C.J.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Psychiatry and Neurochemistry (F.G.-O., T.K., K.B.), Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg; Clinical Neurochemistry Laboratory (F.G.-O., K.B.); Department of Research, Development, Education and Innovation (C.B.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg; Department of Neurology (K.J.), Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; and Department of Psychiatry (T.K.), University of Pittsburgh.
ORCID: 0000-0001-7897-9456

Cecilia Brännmark (C)

From the Department of Laboratory Medicine (T.M.S., C.B., C.J.), Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg; Department of Clinical Genetics and Genomics (T.M.S., C.J.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Psychiatry and Neurochemistry (F.G.-O., T.K., K.B.), Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg; Clinical Neurochemistry Laboratory (F.G.-O., K.B.); Department of Research, Development, Education and Innovation (C.B.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg; Department of Neurology (K.J.), Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; and Department of Psychiatry (T.K.), University of Pittsburgh.

Katarina Jood (K)

From the Department of Laboratory Medicine (T.M.S., C.B., C.J.), Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg; Department of Clinical Genetics and Genomics (T.M.S., C.J.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Psychiatry and Neurochemistry (F.G.-O., T.K., K.B.), Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg; Clinical Neurochemistry Laboratory (F.G.-O., K.B.); Department of Research, Development, Education and Innovation (C.B.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg; Department of Neurology (K.J.), Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; and Department of Psychiatry (T.K.), University of Pittsburgh.

Thomas Karikari (T)

From the Department of Laboratory Medicine (T.M.S., C.B., C.J.), Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg; Department of Clinical Genetics and Genomics (T.M.S., C.J.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Psychiatry and Neurochemistry (F.G.-O., T.K., K.B.), Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg; Clinical Neurochemistry Laboratory (F.G.-O., K.B.); Department of Research, Development, Education and Innovation (C.B.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg; Department of Neurology (K.J.), Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; and Department of Psychiatry (T.K.), University of Pittsburgh.

Kaj Blennow (K)

From the Department of Laboratory Medicine (T.M.S., C.B., C.J.), Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg; Department of Clinical Genetics and Genomics (T.M.S., C.J.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Psychiatry and Neurochemistry (F.G.-O., T.K., K.B.), Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg; Clinical Neurochemistry Laboratory (F.G.-O., K.B.); Department of Research, Development, Education and Innovation (C.B.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg; Department of Neurology (K.J.), Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; and Department of Psychiatry (T.K.), University of Pittsburgh.
ORCID: 0000-0002-1890-4193

Christina Jern (C)

From the Department of Laboratory Medicine (T.M.S., C.B., C.J.), Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg; Department of Clinical Genetics and Genomics (T.M.S., C.J.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Psychiatry and Neurochemistry (F.G.-O., T.K., K.B.), Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg; Clinical Neurochemistry Laboratory (F.G.-O., K.B.); Department of Research, Development, Education and Innovation (C.B.), Region Västra Götaland, Sahlgrenska University Hospital; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg; Department of Neurology (K.J.), Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; and Department of Psychiatry (T.K.), University of Pittsburgh.
ORCID: 0000-0002-7531-2354

Classifications MeSH