Monotherapy Antibiotic Prophylaxis of Lower Extremity Long Bone Type III Open Fractures.

antibiotic prophylaxis lower extremity monotherapy type III open fracture

Journal

The American surgeon
ISSN: 1555-9823
Titre abrégé: Am Surg
Pays: United States
ID NLM: 0370522

Informations de publication

Date de publication:
29 Mar 2024
Historique:
medline: 29 3 2024
pubmed: 29 3 2024
entrez: 29 3 2024
Statut: aheadofprint

Résumé

Gustilo type III open fractures involve extensive soft tissue damage and wound contamination that pose significant infection risks. The historical standard for antibiotic prophylaxis has been cefazolin and gentamicin. We conducted a retrospective cohort study of lower extremity type III open fractures treated with ceftriaxone alone for prophylaxis. Eighty-six patients were identified. Nearly all (98%) were managed with appropriate antibiotics, but only 55 (64%) received prophylaxis within 1 hour. Overall, there were 12 infections. This infection rate was not statistically different than the reported literature (14% vs 19%,

Identifiants

DOI: 10.1177/00031348241241657 PMID: 38551626
pubmed: 38551626
doi: 10.1177/00031348241241657
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

31348241241657

Déclaration de conflit d'intérêts

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Thomas W Robinson (TW)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Corinne E Gautreaux (CE)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Yann-Leei L Lee (YL)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Maryann Mbaka (M)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Christopher M Kinnard (CM)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Andrew C Bright (AC)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Ashley Y Williams (AY)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Nathan M Polite (NM)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Thomas J Capasso (TJ)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Jon D Simmons (JD)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Charles C Butts (CC)

Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, Frederick P. Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.

Classifications MeSH