Disproportion of Corpus Callosum in Fetuses With Malformations of Cortical Development.
corpus callosum
malformations of cortical development
migration disorders
neurosonography
prenatal diagnosis
Journal
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
ISSN: 1550-9613
Titre abrégé: J Ultrasound Med
Pays: England
ID NLM: 8211547
Informations de publication
Date de publication:
01 Apr 2024
01 Apr 2024
Historique:
revised:
28
02
2024
received:
10
09
2023
accepted:
08
03
2024
medline:
1
4
2024
pubmed:
1
4
2024
entrez:
1
4
2024
Statut:
aheadofprint
Résumé
To evaluate corpus callosum (CC) size in fetuses with malformations of cortical development (MCD) and to explore the diagnostic value of three CC length (CCL) ratios in identifying cortical abnormalities. This is a single-center retrospective study in singleton fetuses at 20-37 weeks of gestation between April 2017 and August 2022. The midsagittal plane of the fetal brain was obtained and evaluated for the following variables: length, height, area of the corpus callosum, and relevant markers, including the ratios of corpus callosum length to internal cranial occipitofrontal dimension (CCL/ICOFD), corpus callosum length to femur length (CCL/FL), and corpus callosum length to cerebellar vermian diameter (CCL/VD). Intra-class correlation coefficient (ICC) was used to evaluate measurement consistency. The accuracy of biometric measurements in prediction of MCD was assessed using the area under the receiver-operating-characteristics curves (AUC). Fetuses with MCD had a significantly decreased CCL, height (genu and splenium), and area as compared with those of normal fetuses (P < .05), but there was no significant difference in body height (P = .326). The CCL/ICOFD, CCL/FL, and CCL/VD ratios were significantly decreased in fetuses with MCD when compared with controls (P < .05). The CCL/ICOFD ratio offered the highest predictive accuracy for MCD, yielding an AUC of 0.856 (95% CI: 0.774-0.938, P < .001), followed by CCL/FL ratio (AUC, 0.780 (95% CI: 0.657-0.904), P < .001), CCL/VD ratio (AUC, 0.677 (95% CI: 0.559-0.795), P < .01). The corpus callosum biometric parameters in fetuses with MCD are reduced. The CCL/ICOFD ratio derived from sonographic measurements is considered a promising tool for the prenatal detection of cortical malformations. External validation of these findings and prospective studies are warranted.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Natural Science Foundation of China
ID : 82171938
Organisme : National Natural Science Foundation of China
ID : 82202156
Organisme : Guangzhou Science and Technology Project
ID : 202201011238
Organisme : Guangdong Province Basic and Applied Basic Research Fund Project
ID : 2022A1515220200
Informations de copyright
© 2024 American Institute of Ultrasound in Medicine.
Références
Severino M, Geraldo AF, Utz N, et al. Definitions and classification of malformations of cortical development: practical guidelines. Brain 2020; 143:2874–2894. https://doi.org/10.1093/brain/awaa174.
Barkovich AJ, Guerrini R, Kuzniecky RI, Jackson GD, Dobyns WB. A developmental and genetic classification for malformations of cortical development: update 2012. Brain 2012; 135:1348–1369. https://doi.org/10.1093/brain/aws019.
Raybaud C, Widjaja E. Development and dysgenesis of the cerebral cortex: malformations of cortical development. Neuroimaging Clin N Am 2011; 21:483–543. https://doi.org/10.1016/j.nic.2011.05.014.
Guerrini R, Dobyns WB. Malformations of cortical development: clinical features and genetic causes. Lancet Neurol 2014; 13:710–726. https://doi.org/10.1016/S1474-4422(14)70040-7.
Oegema R, Barakat TS, Wilke M, et al. International consensus recommendations on the diagnostic work‐up for malformations of cortical development. Nat Rev Neurol 2020; 16:618–635. https://doi.org/10.1038/s41582-020-0395-6.
Licchetta L, Vignatelli L, Toni F, et al. Long‐term outcome of epilepsy and cortical malformations due to abnormal migration and postmigrational development: a cohort study. Neurology 2022; 99:e23–e32. https://doi.org/10.1212/wnl.0000000000200352.
Lerman‐Sagie T, Pogledic I, Leibovitz Z, Malinger G. A practical approach to prenatal diagnosis of malformations of cortical development. Eur J Pediatr Neurol 2021; 34:50–61. https://doi.org/10.1016/j.ejpn.2021.08.001.
Brock S, Cools F, Jansen AC. Neuropathology of genetically defined malformations of cortical development – a systematic literature review. Neuropathol Appl Neurobiol 2021; 47:585–602. https://doi.org/10.1111/nan.12696.
Anderson NG, Laurent I, Woodward LJ, Inder TE. Detection of impaired growth of the corpus callosum in premature infants. Pediatrics 2006; 118:951–960. https://doi.org/10.1542/peds.2006-0553.
Fryer SL, Frank LR, Spadoni AD, et al. Microstructural integrity of the corpus callosum linked with neuropsychological performance in adolescents. Brain Cogn 2008; 67:225–233. https://doi.org/10.1016/j.bandc.2008.01.009.
Pashaj S, Merz E, Wellek S. Biometry of the fetal corpus callosum by three‐dimensional ultrasound. Ultrasound Obstet Gynecol 2013; 42:691–698. https://doi.org/10.1002/uog.12501.
Salomon LJ, Alfirevic Z, Berghella V, et al. ISUOG practice guidelines (updated): performance of the routine mid‐trimester fetal ultrasound scan. Ultrasound Obstet Gynecol 2022; 59:840–856. https://doi.org/10.1002/uog.24888.
Paladini D, Malinger G, Birnbaum R, et al. ISUOG practice guidelines (updated): sonographic examination of the fetal central nervous system. Part 2: performance of targeted neurosonography. Ultrasound Obstet Gynecol 2021; 57:661–671. https://doi.org/10.1002/uog.23616.
Witelson SF. Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study. Brain 1989; 112:799–835. https://doi.org/10.1093/brain/112.3.799.
Malinger G, Zakut H. The corpus callosum: normal fetal development as shown by transvaginal sonography. AJR Am J Roentgenol 1993; 161:1041–1043. https://doi.org/10.2214/ajr.161.5.8273605.
Egaña‐Ugrinovic G, Sanz‐Cortés M, Couve‐Pérez C, Figueras F, Gratacós E. Corpus callosum differences assessed by fetal MRI in late‐onset intrauterine growth restriction and its association with neurobehavior. Prenat Diagn 2014; 34:843–849. https://doi.org/10.1002/pd.4381.
Pérez‐Cruz M, Gómez O, Gibert M, et al. Corpus callosum size by neurosonography in fetuses with congenital heart defect and relationship with expected pattern of brain oxygen supply. Ultrasound Obstet Gynecol 2022; 59:220–225. https://doi.org/10.1002/uog.23684.
Counsell SJ, Edwards AD, Chew AT, et al. Specific relations between neurodevelopmental abilities and white matter microstructure in children born preterm. Brain 2008; 131:3201–3208. https://doi.org/10.1093/brain/awn268.
Dorovini‐Zis K, Dolman CL. Gestational development of brain. Arch Pathol Lab Med 1977; 101:192–195.
Barkovich MJ, Barkovich AJ. MR imaging of normal brain development. Neuroimaging Clin N Am 2019; 29:325–337. https://doi.org/10.1016/j.nic.2019.03.007.
Tarui T, Madan N, Farhat N, et al. Disorganized patterns of sulcal position in fetal brains with agenesis of corpus callosum. Cereb Cortex 2018; 28:3192–3203. https://doi.org/10.1093/cercor/bhx191.
Widjaja E, Blaser S, Miller E, et al. Evaluation of subcortical white matter and deep white matter tracts in malformations of cortical development. Epilepsia 2007; 48:1460–1469. https://doi.org/10.1111/j.1528-1167.2007.01105.x.
Andrade CS, Leite CC, Otaduy MC, et al. Diffusion abnormalities of the corpus callosum in patients with malformations of cortical development and epilepsy. Epilepsy Res 2014; 108:1533–1542. https://doi.org/10.1016/j.eplepsyres.2014.08.023.
Tepper R, Leibovitz Z, Garel C, Sukenik‐Halevy R. A new method for evaluating short fetal corpus callosum. Prenat Diagn 2019; 39:1283–1290. https://doi.org/10.1002/pd.5598.
Tsur A, Weisz B, Rosenblat O, et al. Personalized charts for the fetal corpus callosum length. J Matern Fetal Neonatal Med 2019; 32:3931–3938. https://doi.org/10.1080/14767058.2018.1479389.
Sidman RL, Rakic P. Neuronal migration, with special reference to developing human brain: a review. Brain Res 1973; 62:1–35. https://doi.org/10.1016/0006-8993(73)90617-3.
Krajden Haratz K, Birnbaum R, Kidron D, et al. Malformation of cortical development with abnormal cortex: early ultrasound diagnosis between 14 and 24 weeks of gestation. Ultrasound Obstet Gynecol 2023; 61:559–565. https://doi.org/10.1002/uog.26139.
Pooh RK, Machida M, Nakamura T, et al. Increased Sylvian fissure angle as early sonographic sign of malformation of cortical development. Ultrasound Obstet Gynecol 2019; 54:199–206. https://doi.org/10.1002/uog.20171.
Montaguti E, Bellussi F, Rizzo R, et al. Sylvian fossa sonographic measurements in 18 to 23 weeks fetuses with and without cerebral malformations. Am J Obstet Gynecol 2021; 3:100357. https://doi.org/10.1016/j.ajogmf.2021.100357.
Paules C, Miranda J, Policiano C, et al. Fetal neurosonography detects differences in cortical development and corpus callosum in late‐onset small fetuses. Ultrasound Obstet Gynecol 2021; 58:42–47. https://doi.org/10.1002/uog.23592.