Deep brain stimulation of the subthalamic nucleus restores spatial reversal learning in patients with Parkinson's disease.
Parkinson’s disease
deep brain stimulation
reversal learning
spatial learning
subthalamic nucleus
Journal
Brain communications
ISSN: 2632-1297
Titre abrégé: Brain Commun
Pays: England
ID NLM: 101755125
Informations de publication
Date de publication:
2024
2024
Historique:
received:
01
11
2022
revised:
04
01
2024
accepted:
26
02
2024
medline:
1
4
2024
pubmed:
1
4
2024
entrez:
1
4
2024
Statut:
epublish
Résumé
Spatial learning and navigation are supported by distinct memory systems in the human brain such as the hippocampus-based navigational system and the striatum-cortex-based system involved in motor sequence, habit and reversal learning. Here, we studied the role of subthalamic circuits in hippocampus-associated spatial memory and striatal-associated spatial reversal learning formation in patients with Parkinson's disease, who underwent a deep brain stimulation of the subthalamic nucleus. Deep brain stimulation patients (Parkinson's disease-subthalamic nucleus:
Identifiants
pubmed: 38560516
doi: 10.1093/braincomms/fcae068
pii: fcae068
pmc: PMC10979721
doi:
Types de publication
Journal Article
Langues
eng
Pagination
fcae068Informations de copyright
© The Author(s) 2024. Published by Oxford University Press on behalf of the Guarantors of Brain.
Déclaration de conflit d'intérêts
The authors report no competing interests.