Mining the microbiome of Lake Afdera to gain insights into microbial diversity and biosynthetic potential.

Lake Afdera biosynthetic gene clusters metagenomics microbiome secondary metabolites shotgun sequencing

Journal

FEMS microbes
ISSN: 2633-6685
Titre abrégé: FEMS Microbes
Pays: England
ID NLM: 9918227365806676

Informations de publication

Date de publication:
2024
Historique:
received: 02 09 2023
revised: 24 01 2024
accepted: 05 03 2024
medline: 1 4 2024
pubmed: 1 4 2024
entrez: 1 4 2024
Statut: epublish

Résumé

Microorganisms inhabiting hypersaline environments have received significant attention due to their ability to thrive under poly-extreme conditions, including high salinity, elevated temperatures and heavy metal stress. They are believed to possess biosynthetic gene clusters (BGCs) that encode secondary metabolites as survival strategy and offer potential biotechnological applications. In this study, we mined BGCs in shotgun metagenomic sequences generated from Lake Afdera, a hypersaline lake in the Afar Depression, Ethiopia. The microbiome of Lake Afdera is predominantly bacterial, with

Identifiants

pubmed: 38560625
doi: 10.1093/femsmc/xtae008
pii: xtae008
pmc: PMC10979467
doi:

Types de publication

Journal Article

Langues

eng

Pagination

xtae008

Informations de copyright

© The Author(s) 2024. Published by Oxford University Press on behalf of FEMS.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests

Auteurs

Ermias Sissay Balcha (ES)

School of Medical Laboratory Science, College of Health Sciences, Hawassa University, 16417, Hawassa, Ethiopia.
Biotechnology and Bioprocess Center of Excellence, College of Biological and Chemical Engineering, Addis Ababa Science and Technology University, 16417, Addis Ababa, Ethiopia.

Michael C Macey (MC)

Astrobiology OU, School of Environment, Earth and Ecosystem Sciences, The Open University, Milton Keynes, MK7 6AA, United Kingdom.

Mesfin Tafesse Gemeda (MT)

Biotechnology and Bioprocess Center of Excellence, College of Biological and Chemical Engineering, Addis Ababa Science and Technology University, 16417, Addis Ababa, Ethiopia.

Barbara Cavalazzi (B)

Dipartimento di Scienze Biologiche, Geologiche e Ambientali, Università di Bologna, Bologna, Italy.
Department of Geology, University of Johannesburg, Johannesburg, South Africa.

Adugna Abdi Woldesemayat (AA)

Biotechnology and Bioprocess Center of Excellence, College of Biological and Chemical Engineering, Addis Ababa Science and Technology University, 16417, Addis Ababa, Ethiopia.

Classifications MeSH