Momentum of hope: The journey toward a universal TB vaccine.

Mtb Mycobacterium tuberculosis TB TB vaccine Tuberculosis infectious diseases

Journal

Tropical doctor
ISSN: 1758-1133
Titre abrégé: Trop Doct
Pays: England
ID NLM: 1301706

Informations de publication

Date de publication:
02 Apr 2024
Historique:
medline: 2 4 2024
pubmed: 2 4 2024
entrez: 2 4 2024
Statut: aheadofprint

Résumé

In addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in increasing protection against TB in adults with latent infections. These advancements represent a significant leap forward in the quest to control and eventually eradicate TB. This piece highlights the necessity of continued investment in vaccine research and development. The pursuit of more effective TB vaccines, capable of providing broader protection across all age groups, is paramount. This effort not only aligns with the WHO's End TB Strategy but also offers hope for a future where TB is no longer a global health crisis.

Identifiants

pubmed: 38562088
doi: 10.1177/00494755241244833
doi:

Types de publication

Letter

Langues

eng

Sous-ensembles de citation

IM

Pagination

494755241244833

Déclaration de conflit d'intérêts

Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Bashar Haruna Gulumbe (BH)

Department of Microbiology, Faculty of Science, Federal University Birnin-Kebbi, Birnin Kebbi, Nigeria.

Aminu Shehu (A)

Department of Microbiology, Faculty of Life Sciences, Bayero University, Kano, Nigeria.

Classifications MeSH