Momentum of hope: The journey toward a universal TB vaccine.
Mtb
Mycobacterium tuberculosis
TB
TB vaccine
Tuberculosis
infectious diseases
Journal
Tropical doctor
ISSN: 1758-1133
Titre abrégé: Trop Doct
Pays: England
ID NLM: 1301706
Informations de publication
Date de publication:
02 Apr 2024
02 Apr 2024
Historique:
medline:
2
4
2024
pubmed:
2
4
2024
entrez:
2
4
2024
Statut:
aheadofprint
Résumé
In addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in increasing protection against TB in adults with latent infections. These advancements represent a significant leap forward in the quest to control and eventually eradicate TB. This piece highlights the necessity of continued investment in vaccine research and development. The pursuit of more effective TB vaccines, capable of providing broader protection across all age groups, is paramount. This effort not only aligns with the WHO's End TB Strategy but also offers hope for a future where TB is no longer a global health crisis.
Identifiants
pubmed: 38562088
doi: 10.1177/00494755241244833
doi:
Types de publication
Letter
Langues
eng
Sous-ensembles de citation
IM
Pagination
494755241244833Déclaration de conflit d'intérêts
Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.