Physical activity following pulmonary embolism and clinical correlates in selected patients: a cross-sectional study.

activity cardiac function exercise capacity pulmonary embolism quality of life venous thromboembolism

Journal

Research and practice in thrombosis and haemostasis
ISSN: 2475-0379
Titre abrégé: Res Pract Thromb Haemost
Pays: United States
ID NLM: 101703775

Informations de publication

Date de publication:
Feb 2024
Historique:
received: 01 02 2024
accepted: 13 02 2024
medline: 2 4 2024
pubmed: 2 4 2024
entrez: 2 4 2024
Statut: epublish

Résumé

There is limited knowledge regarding physical activity and clinical correlates among people who have suffered a pulmonary embolism (PE). To assess physical activity levels after PE and potential clinical correlates. One hundred forty-five individuals free of major comorbidities were recruited at a mean of 23 months (range, 6-72) after PE diagnosis. Physical activity was assessed by steps/day on the Sensewear monitor for 7 consecutive days, exercise capacity with the incremental shuttle walk test, and cardiac function with left ventricular ejection fraction (LVEF). The association between physical activity and other variables was analyzed by a mixed-effects model. Participants achieved a mean of 6494 (SD, 3294; range, 1147-18.486) steps/day. The mixed-effects model showed that physical activity was significantly associated with exercise capacity (β-coefficient, 0.04; 95% CI, 0.03-0.05) and LVEF (β-coefficient, -0.81; 95% CI, -1.42 to -0.21). The analysis further showed that men became less physically active with increasing age (β-coefficient, -0.14; 95% CI, -0.24 to -0.04), whereas no change with age could be detected for women. In selected post-PE patients, physical activity seems to be associated with exercise capacity and LVEF but not with quality of life, dyspnea, or characteristics of the initial PE. Men appear to become less physically active with increasing age.

Sections du résumé

Background UNASSIGNED
There is limited knowledge regarding physical activity and clinical correlates among people who have suffered a pulmonary embolism (PE).
Objectives UNASSIGNED
To assess physical activity levels after PE and potential clinical correlates.
Methods UNASSIGNED
One hundred forty-five individuals free of major comorbidities were recruited at a mean of 23 months (range, 6-72) after PE diagnosis. Physical activity was assessed by steps/day on the Sensewear monitor for 7 consecutive days, exercise capacity with the incremental shuttle walk test, and cardiac function with left ventricular ejection fraction (LVEF). The association between physical activity and other variables was analyzed by a mixed-effects model.
Results UNASSIGNED
Participants achieved a mean of 6494 (SD, 3294; range, 1147-18.486) steps/day. The mixed-effects model showed that physical activity was significantly associated with exercise capacity (β-coefficient, 0.04; 95% CI, 0.03-0.05) and LVEF (β-coefficient, -0.81; 95% CI, -1.42 to -0.21). The analysis further showed that men became less physically active with increasing age (β-coefficient, -0.14; 95% CI, -0.24 to -0.04), whereas no change with age could be detected for women.
Conclusion UNASSIGNED
In selected post-PE patients, physical activity seems to be associated with exercise capacity and LVEF but not with quality of life, dyspnea, or characteristics of the initial PE. Men appear to become less physically active with increasing age.

Identifiants

pubmed: 38562511
doi: 10.1016/j.rpth.2024.102366
pii: S2475-0379(24)00055-4
pmc: PMC10982567
doi:

Types de publication

Journal Article

Langues

eng

Pagination

102366

Informations de copyright

© 2024 The Author(s).

Auteurs

Stacey Haukeland-Parker (S)

Department of Physical Medicine and Rehabilitation, Østfold Hospital Trust, Grålum, Norway.
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Øyvind Jervan (Ø)

Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Department of Cardiology, Østfold Hospital Trust, Grålum, Norway.

Waleed Ghanima (W)

Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Department of Research, Emergency Medicine and Hematooncology, Østfold Hospital Trust, Grålum, Norway.
Department of Hematology, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Martijn A Spruit (MA)

Department of Research and Development, CIRO+, Horn, the Netherlands.
Department of Respiratory Medicine, Maastricht University Medical Center, Maastricht, the Netherlands.
School of Nutrition and Translational Research in Metabolism, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands.

René Holst (R)

Department of Research, Emergency Medicine and Hematooncology, Østfold Hospital Trust, Grålum, Norway.
Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

Mazdak Tavoly (M)

Department of Research, Emergency Medicine and Hematooncology, Østfold Hospital Trust, Grålum, Norway.
Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.

Jostein Gleditsch (J)

Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Department of Radiology, Østfold Hospital Trust, Grålum, Norway.

Hege Hølmo Johannessen (HH)

Department of Physical Medicine and Rehabilitation, Østfold Hospital Trust, Grålum, Norway.
Department of Health, Welfare and Organization, Østfold University College, Fredrikstad, Norway.

Classifications MeSH