Afadin-nectin forces its way to the front.


Journal

The Journal of cell biology
ISSN: 1540-8140
Titre abrégé: J Cell Biol
Pays: United States
ID NLM: 0375356

Informations de publication

Date de publication:
06 May 2024
Historique:
medline: 2 4 2024
pubmed: 2 4 2024
entrez: 2 4 2024
Statut: ppublish

Résumé

Force transmission at cell-cell junctions critically regulates embryogenesis, tissue homeostasis, and diseases including cancer. The cadherin-catenin linkage has been considered the keystone of junctional force transmission, but new findings challenge this paradigm, arguing instead that the nectin-afadin linkage plays the more important role in mature junctions in the intestinal epithelium.

Identifiants

pubmed: 38563860
pii: 276676
doi: 10.1083/jcb.202403177
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 Sebbagh and Schwartz.

Auteurs

Michael Sebbagh (M)

Aix-Marseille University, Inserm, DyNaMo, Turing Centre of Living Systems, Marseille, France.

Martin A Schwartz (MA)

Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine and Departments of Cell Biology and Biomedical Engineering, Yale University, New Haven, CT, USA.

Classifications MeSH