A multicenter prospective observational study appraising the effectiveness of the Supera stent after subintimal recanalization of femoro-popliteal artery occlusion: The SUPERSUB II study.

Supera stent endovascular therapy femoropopliteal disease peripheral artery disease stent subintimal angioplasty

Journal

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
ISSN: 1522-726X
Titre abrégé: Catheter Cardiovasc Interv
Pays: United States
ID NLM: 100884139

Informations de publication

Date de publication:
02 Apr 2024
Historique:
revised: 04 02 2024
received: 28 09 2023
accepted: 19 03 2024
medline: 3 4 2024
pubmed: 3 4 2024
entrez: 3 4 2024
Statut: aheadofprint

Résumé

Complex femoropopliteal artery disease represents a challenge. The Supera stent holds the promise of improving the results of endovascular therapy for complex femoropopliteal disease. We aimed at appraising the early and long-term effectiveness of the Supera stent after successful subintimal angioplasty (SuperSUB strategy) for complex femoropopliteal lesions. We conducted a multicenter, prospective, single-arm observational study including consecutive patients at participating centers in whom Supera was implanted after successful subintimal angioplasty for complex femoropopliteal lesions. A total of 92 patients were included Femoropopliteal arteries were the most common target, and lesion length was 261 ± 102 mm. Most procedures were technically demanding, with antegrade femoral access in 35 (38%) and retrograde distal access in 55 (60%). Supera stent length was 281 ± 111 mm, with 4, 5, and 6 mm devices being most commonly used: 32 (35%), 35 (38%), and 23 (25%), respectively. Technical success was achieved in 100% of subjects, as was clinical success (per subject), whereas procedural success (per subject) was obtained in 98%. At 24 months, freedom from clinically driven target lesion revascularization was 93%, whereas primary patency was 87%. When compared with a similar historical cohort, Supera stent use appeared to be associated with a reduction in resources. Use of Supera stent after successful subintimal recanalization of complex lower limb arterial lesions yields favorable procedural results, which are maintained over follow-up, and are associated also with a favorable resource use profile.

Sections du résumé

BACKGROUND BACKGROUND
Complex femoropopliteal artery disease represents a challenge. The Supera stent holds the promise of improving the results of endovascular therapy for complex femoropopliteal disease.
AIMS OBJECTIVE
We aimed at appraising the early and long-term effectiveness of the Supera stent after successful subintimal angioplasty (SuperSUB strategy) for complex femoropopliteal lesions.
METHODS METHODS
We conducted a multicenter, prospective, single-arm observational study including consecutive patients at participating centers in whom Supera was implanted after successful subintimal angioplasty for complex femoropopliteal lesions.
RESULTS RESULTS
A total of 92 patients were included Femoropopliteal arteries were the most common target, and lesion length was 261 ± 102 mm. Most procedures were technically demanding, with antegrade femoral access in 35 (38%) and retrograde distal access in 55 (60%). Supera stent length was 281 ± 111 mm, with 4, 5, and 6 mm devices being most commonly used: 32 (35%), 35 (38%), and 23 (25%), respectively. Technical success was achieved in 100% of subjects, as was clinical success (per subject), whereas procedural success (per subject) was obtained in 98%. At 24 months, freedom from clinically driven target lesion revascularization was 93%, whereas primary patency was 87%. When compared with a similar historical cohort, Supera stent use appeared to be associated with a reduction in resources.
CONCLUSION CONCLUSIONS
Use of Supera stent after successful subintimal recanalization of complex lower limb arterial lesions yields favorable procedural results, which are maintained over follow-up, and are associated also with a favorable resource use profile.

Identifiants

pubmed: 38566517
doi: 10.1002/ccd.31028
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Fondazione Italiana Vascolare Onlus
Organisme : Società Italiana di Diagnostica Vascolare

Informations de copyright

© 2024 Wiley Periodicals LLC.

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Auteurs

Luis Mariano Palena (LM)

Interventional Radiology Unit, Endovascular Interventions & Research, Foot & Ankle Clinic, Policlinico, Abano Terme, Italy.
Endovascular Surgery Unit, Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy.

Giacomo Isernia (G)

Vascular Surgery Unit, A.O. Hospital Santa Maria della Misericordia, Perugia, Italy.

Gianbattista Parlani (G)

Vascular Surgery Unit, A.O. Hospital Santa Maria della Misericordia, Perugia, Italy.

Pierfrancesco Veroux (P)

Vascular Surgery Unit, AOU Policlinico G. Rodolico - San Marco, Catania, Italy.

Ilaria Ficarelli (I)

Vascular Surgery Unit, A.O.R.N. Cardarelli, Naples, Italy.

Arian Frascheri (A)

Hemodynamics O.U., Hospital Sant'Antonio Abate, Erice, Italy.

Aldo Pischedda (A)

Interventional Radiology Unit, A.O.U. Sassari, Sassari, Italy.

Lorenzo Patrone (L)

Vascular and Interventional Radiology Unit, London North-West University NHS Trust-London, London, UK.

Carlo Patrizio Dionisi (CP)

Vascular Surgery Unit, A.O. Cardinale Panico, Tricase, Italy.

Roberto Cianni (R)

Interventional Radiology Unit, A.O. San Camillo Forlanini, Rome, Italy.

Flavio Airoldi (F)

Interventional Cadiovascolar Unit, IRCCS Multimedica, Sesto San Giovanni, Milan, Italy.

Pietro Landino (P)

Interventional Cardiology Unit, Casa di Cura Maddaloni, Maddaloni, Italy.

Andrès Kleiban (A)

Endovascular Areas, Instituto Medico Ceniclar, Rosario, Argentina.

Pietro Filauri (P)

Interventional Radiology Unit, Avezzano Hospital, Avezzano, Italy.

Giovanni Passalacqua (G)

Interventional Radiology Unit, A.O. Santa Maria di Terni, Terni, Italy.

Pier Luigi Antignani (PL)

Fondazione Italiana Vascolare (FIV), Rome, Italy.

Enrico De Rose (E)

EndocoreLab Srl, CRO, Albignasego, Padua, Italy.

Albert Valls (A)

EndocoreLab Srl, CRO, Albignasego, Padua, Italy.

Giuseppe Biondi-Zoccai (G)

Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy.
Cardiology Unit, Santa Maria Goretti Hospital, Latina, Italy.

Marco Manzi (M)

Interventional Radiology Unit, Endovascular Interventions & Research, Foot & Ankle Clinic, Policlinico, Abano Terme, Italy.

Classifications MeSH