The transcription factor
DFNA15
Pou4f3
hair cell maturation
hair cell survival
hearing loss
Journal
Frontiers in cellular neuroscience
ISSN: 1662-5102
Titre abrégé: Front Cell Neurosci
Pays: Switzerland
ID NLM: 101477935
Informations de publication
Date de publication:
2024
2024
Historique:
received:
11
01
2024
accepted:
26
02
2024
medline:
3
4
2024
pubmed:
3
4
2024
entrez:
3
4
2024
Statut:
epublish
Résumé
Hair cells (HCs) of the cochlea are responsible for sound transduction and hearing perception in mammals. Genetic mutations in the transcription factor Therefore, using the inducible CreER-loxP system, we deleted Elevated auditory brainstem response thresholds and significant HC loss were detected in mice with
Identifiants
pubmed: 38566840
doi: 10.3389/fncel.2024.1369282
pmc: PMC10985149
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1369282Informations de copyright
Copyright © 2024 Singh, Randle, Walters and Cox.
Déclaration de conflit d'intérêts
BC is a consultant for Turner Scientific, LLC, and previously had sponsored research contracts with Decibel Therapeutics, Inc. and Otonomy, Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.