A case of Adult-onset Acute Flaccid Myelitis Accompanied by Rhombencephalitis which First Presented with Prominent Psychiatric Symptoms and Dysautonomia Mimicking Anti-N-methyl-d-aspartate Receptor Encephalitis.

NMDAR encephalitis acute flaccid myelitis autonomic dysfunction cardiac arrest rhombencephalitis

Journal

Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241

Informations de publication

Date de publication:
02 Apr 2024
Historique:
medline: 4 4 2024
pubmed: 4 4 2024
entrez: 3 4 2024
Statut: aheadofprint

Résumé

A 44-year-old woman with a subacute onset of an altered mental status, urinary retention, and fluctuating blood pressure was initially diagnosed with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis, meeting the criteria of Graus et al. Cardiac arrest occurred, which required pacemaker placement. She subsequently showed profound flaccid limb paralysis, with magnetic resonance imaging demonstrating focal necrotic lesions localized in the anterior horn of the longitudinal segments of the spinal cord and in the pontine tegmentum. Enteroviruses or autoimmune encephalitis-associated autoantibodies were not detected. We herein report a case of acute flaccid myelitis with profound psychiatric symptoms and dysautonomia, resembling NMDAR encephalitis.

Identifiants

pubmed: 38569911
doi: 10.2169/internalmedicine.2767-23
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Hiroyuki Sumikura (H)

Department of Neurology, Osaka General Medical Center, Japan.

Mai Ito (M)

Department of Neurology, Osaka General Medical Center, Japan.

Takuma Sato (T)

Department of Neurology, Osaka General Medical Center, Japan.

Naoki Hatayama (N)

Department of Neurology, Osaka General Medical Center, Japan.

Tomohiro Fujioka (T)

Department of Neurology, Osaka General Medical Center, Japan.

Nozomi Nagashima (N)

Department of Neurology, Osaka General Medical Center, Japan.

Yuki Shimada (Y)

Department of Neurology, Osaka General Medical Center, Japan.

Isao Fukasaka (I)

Department of Neurology, Osaka General Medical Center, Japan.

Mikito Shimizu (M)

Department of Neurology, Osaka General Medical Center, Japan.

Kyoko Higashida (K)

Department of Neurology, Osaka General Medical Center, Japan.

Taku Hoshi (T)

Department of Neurology, Osaka General Medical Center, Japan.

Keiko Tanaka (K)

Department of Animal Model Development, Brain Research Institute, Niigata University, Japan.

Manabu Sakaguchi (M)

Department of Neurology, Osaka General Medical Center, Japan.

Classifications MeSH