Emerging and re-emerging infectious diseases in pregnant women in an amazonian region: a large retrospective study from French Guiana.

Amazonia Arboviruses Emerging infectious diseases Pregnancy Syphilis

Journal

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
ISSN: 1435-4373
Titre abrégé: Eur J Clin Microbiol Infect Dis
Pays: Germany
ID NLM: 8804297

Informations de publication

Date de publication:
04 Apr 2024
Historique:
received: 03 10 2023
accepted: 18 03 2024
medline: 4 4 2024
pubmed: 4 4 2024
entrez: 4 4 2024
Statut: aheadofprint

Résumé

Over the past decade, the Amazon basin has faced numerous infectious epidemics. Our comprehension of the actual extent of these infections during pregnancy remains limited. This study aimed to clarify the clinical and epidemiological features of emerging and re-emerging infectious diseases during pregnancy in western French Guiana and along the Maroni River over the previous nine years. This retrospective cohort study enrolled pregnant women living in west French Guiana territory and giving birth in the only local referral center after 22 weeks of gestation between 2013 and 2021. Data on symptomatic or asymptomatic biologically confirmed emerging or re-emerging diseases during pregnancy was collected. Six epidemic waves were experienced during the study period, including 498 confirmed Zika virus infections (2016), 363 SARS-CoV-2 infections (2020-2021), 87 chikungunya virus infections (2014), 76 syphilis infections (2013-2021), and 60 dengue virus infections (2013-2021) at different gestational ages. Furthermore, 1.1% (n = 287) and 1.4% (n = 350) of pregnant women in west French Guiana were living with HIV and HTLV, respectively. During the study period, at least 5.5% (n = 1,371) faced an emerging or re-emerging infection during pregnancy. These results highlight the diversity, abundance, and dynamism of emerging and re-emerging infectious agents faced by pregnant women in the Amazon basin. Considering the maternal and neonatal adverse outcomes associated with these infections, increased efforts are required to enhance diagnosis, reporting, and treatment of these conditions.

Identifiants

pubmed: 38573394
doi: 10.1007/s10096-024-04813-y
pii: 10.1007/s10096-024-04813-y
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

Najeh Hcini (N)

Department of Obstetrics and Gynecology, West French Guiana Hospital Center, Saint-Laurent-du-Maroni, French Guiana. n.hcini@ch-ouestguyane.fr.
DFR Santé Université Guyane, CIC Inserm 1424, Cayenne, France. n.hcini@ch-ouestguyane.fr.

Véronique Lambert (V)

Department of Obstetrics and Gynecology, West French Guiana Hospital Center, Saint-Laurent-du-Maroni, French Guiana.

Jean-François Carod (JF)

Department of Biology, West French Guiana Hospital Center, Saint-Laurent-du-Maroni, French Guiana.

Meredith Mathieu (M)

Department of Obstetrics and Gynecology, West French Guiana Hospital Center, Saint-Laurent-du-Maroni, French Guiana.

Gabriel Carles (G)

Department of Obstetrics and Gynecology, West French Guiana Hospital Center, Saint-Laurent-du-Maroni, French Guiana.

Olivier Picone (O)

Service de Gynécologie-Obstétrique, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, Université de Paris, Inserm IAME-U1137, Colombes Cedex, Paris, France.
Université de Paris, Colombes Cedex, Paris, France.
Inserm IAME-U1137, Paris, France.
Groupe de Recherche sur les Infections pendant la Grossesse (GRIG), Vélizy, France.
FHU Prema, Paris, France.

Jeanne Sibiude (J)

Service de Gynécologie-Obstétrique, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, Université de Paris, Inserm IAME-U1137, Colombes Cedex, Paris, France.
Université de Paris, Colombes Cedex, Paris, France.
Inserm IAME-U1137, Paris, France.
Groupe de Recherche sur les Infections pendant la Grossesse (GRIG), Vélizy, France.
FHU Prema, Paris, France.

Leo Pomar (L)

School of Health Sciences (HESAV), HES-SO University of Applied Sciences and Arts Western Switzerland, 1011, Lausanne, Switzerland.
Ultrasound and Fetal medicine, Department Woman-mother-child, Lausanne University Hospital and Lausanne University, 1011, Lausanne, Switzerland.

Mathieu Nacher (M)

Centre Hospitalier de Cayenne, Cayenne, French Guiana.

Classifications MeSH