Identification of high lead exposure locations in Ohio at the census tract scale using a generalizable geospatial hotspot approach.
Analyses
Child Exposure/Health
Environmental Justice
Geospatial
Metals
Journal
Journal of exposure science & environmental epidemiology
ISSN: 1559-064X
Titre abrégé: J Expo Sci Environ Epidemiol
Pays: United States
ID NLM: 101262796
Informations de publication
Date de publication:
04 Apr 2024
04 Apr 2024
Historique:
received:
12
09
2023
accepted:
14
03
2024
revised:
13
03
2024
medline:
5
4
2024
pubmed:
5
4
2024
entrez:
4
4
2024
Statut:
aheadofprint
Résumé
Lead is a persistent, ubiquitous pollutant whose historical sources have been largely addressed through regulation and voluntary actions. The United States (U.S.) has achieved significant decreases in children's blood lead levels (BLL) over the past 40 years; however, there is no known safe level of Pb exposure. Some communities continue to be disproportionately impacted by exposure to Pb, including Black children and families living in older homes. To identify Ohio (OH) census tracts with children exposed to Pb and evaluate potential exposure determinants. We obtained individual children's blood Pb data from 2005-2018 in OH. The percent of children with elevated BLL (EBLL) was calculated for OH census tracts using three blood Pb reference values (3.5, 5, and 10 µg/dL). Getis-Ord Gi* geospatial hotspot or top 20th percentile methodologies were then applied to identify "hotspots." Findings across multiple time periods and blood Pb reference values were evaluated and compared with existing Pb exposure indices and models. Consistency was observed across different blood Pb reference values, with the main hotspots identified at 3.5 µg/dL, also identified at 5 and 10 µg/dL. Substantial gains in public health were demonstrated, with the biggest decreases in the number of census tracts with EBLL observed between 2008-2010 and 2011-2013. Across OH, 355 census tracts (of 2850) were identified as hotspots across 17 locations, with the majority in the most populated cites. Generally, old housing and sociodemographic factors were indicators of these EBLL hotspots. A smaller number of hotspots were not associated with these exposure determinants. Variables of race, income, and education level were all strong predictors of hotspots. The Getis-Ord Gi* geospatial hotspot analysis can inform local investigations into potential Pb exposures for children living in OH. The successful application of a generalizable childhood blood Pb methodology at the census tract scale provides results that are more readily actionable. The moderate agreement of the measured blood Pb results with public Pb indices provide confidence that these indices can be used in the absence of available blood Pb surveillance data. While not a replacement for universal blood Pb testing, a consistent approach can be applied to identify areas where Pb exposure may be problematic.
Sections du résumé
BACKGROUND
BACKGROUND
Lead is a persistent, ubiquitous pollutant whose historical sources have been largely addressed through regulation and voluntary actions. The United States (U.S.) has achieved significant decreases in children's blood lead levels (BLL) over the past 40 years; however, there is no known safe level of Pb exposure. Some communities continue to be disproportionately impacted by exposure to Pb, including Black children and families living in older homes.
OBJECTIVE
OBJECTIVE
To identify Ohio (OH) census tracts with children exposed to Pb and evaluate potential exposure determinants.
METHODS
METHODS
We obtained individual children's blood Pb data from 2005-2018 in OH. The percent of children with elevated BLL (EBLL) was calculated for OH census tracts using three blood Pb reference values (3.5, 5, and 10 µg/dL). Getis-Ord Gi* geospatial hotspot or top 20th percentile methodologies were then applied to identify "hotspots." Findings across multiple time periods and blood Pb reference values were evaluated and compared with existing Pb exposure indices and models.
RESULTS
RESULTS
Consistency was observed across different blood Pb reference values, with the main hotspots identified at 3.5 µg/dL, also identified at 5 and 10 µg/dL. Substantial gains in public health were demonstrated, with the biggest decreases in the number of census tracts with EBLL observed between 2008-2010 and 2011-2013. Across OH, 355 census tracts (of 2850) were identified as hotspots across 17 locations, with the majority in the most populated cites. Generally, old housing and sociodemographic factors were indicators of these EBLL hotspots. A smaller number of hotspots were not associated with these exposure determinants. Variables of race, income, and education level were all strong predictors of hotspots.
IMPACT STATEMENT
UNASSIGNED
The Getis-Ord Gi* geospatial hotspot analysis can inform local investigations into potential Pb exposures for children living in OH. The successful application of a generalizable childhood blood Pb methodology at the census tract scale provides results that are more readily actionable. The moderate agreement of the measured blood Pb results with public Pb indices provide confidence that these indices can be used in the absence of available blood Pb surveillance data. While not a replacement for universal blood Pb testing, a consistent approach can be applied to identify areas where Pb exposure may be problematic.
Identifiants
pubmed: 38575709
doi: 10.1038/s41370-024-00666-x
pii: 10.1038/s41370-024-00666-x
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.
Références
Mielke HW, Gonzales CR, Powell ET, Egendorf SP. Lead in air, soil, and blood: Pb poisoning in a changing world. Int J Environ Res Public Health. 2022;19:9500. https://doi.org/10.3390/ijerph19159500 .
doi: 10.3390/ijerph19159500
pubmed: 35954853
pmcid: 9368099
Wang Z, Wade AM, Richter DD, Stapleton HM, Kaste JM, Vengosh A. Legacy of anthropogenic lead in urban soils: co-occurrence with metal(loids) and fallout radionuclides, isotopic fingerprinting, and in vitro bioaccessibility. Sci Total Environ. 2022;806:151276. https://doi.org/10.1016/j.scitotenv.2021.151276 .
doi: 10.1016/j.scitotenv.2021.151276.
pubmed: 34717995
Arnold OM, Liu J. Blood lead levels ≤10 micrograms/deciliter and executive functioning across childhood development: a systematic review. Neurotoxicol Teratol. 2020;80:106888. https://doi.org/10.1016/j.ntt.2020.106888 .
doi: 10.1016/j.ntt.2020.106888
pubmed: 32387536
pmcid: 7923389
Lanphear BP, Hornung R, Khoury J, Yolton K, Baghurst P, Bellinger DC, et al. Low-level environmental lead exposure and children’s intellectual function: an international pooled analysis. Environ Health Perspect. 2005;113:894–9. https://doi.org/10.1289/ehp.7688 .
doi: 10.1289/ehp.7688
pubmed: 16002379
pmcid: 1257652
Rocha A, Trujillo KA. Neurotoxicity of low-level lead exposure: History, mechanisms of action, and behavioral effects in humans and preclinical models. Neurotox. 2019;73:58–80. https://doi.org/10.1016/j.neuro.2019.02.021 .
doi: 10.1016/j.neuro.2019.02.021
Sears CG, Lanphear BP, Xu Y, Chen A, Yolton K, Braun JM. Identifying periods of heightened susceptibility to lead exposure in relation to behavioral problems. J Expo Sci Environ Epidemiol. 2022;32:1–9. https://doi.org/10.1038/s41370-021-00389-3 .
doi: 10.1038/s41370-021-00389-3
pubmed: 34728761
Egan KB, Cornwell CR, Courtney JG, Ettinger AS. Blood lead levels in U.S. children ages 1–11 years, 1976–2016. Environ Health Perspect. 2021;129:37003. https://doi.org/10.1289/EHP7932 .
doi: 10.1289/EHP7932
pubmed: 33730866
Centers for Disease Control and Prevention (CDC). Blood Lead Reference Value. 2022. https://www.cdc.gov/nceh/lead/data/blood-lead-reference-value.htm . Accessed 2 February 2023.
Teye SO, Yanosky JD, Cuffee Y, Weng X, Luquis R, Farace E, et al. Exploring persistent racial/ethnic disparities in lead exposure among American children aged 1-5 years: results from NHANES 1999-2016. Int Arch Occup Environ Health. 2021;94:723–30. https://doi.org/10.1007/s00420-020-01616-4 .
doi: 10.1007/s00420-020-01616-4
pubmed: 33394180
Hauptman M, Niles JK, Gudin J, Kaufman HW. Individual- and community-level factors associated with detectable and elevated blood lead levels in US children: results from a National Clinical Laboratory. JAMA Pediatr. 2021;175:1252–60. https://doi.org/10.1001/jamapediatrics.2021.3518 .
doi: 10.1001/jamapediatrics.2021.3518
pubmed: 34570188
Breysse PN, Cascio WE, Geller AM, Choiniere CJ, Ammon M. Targeting coordinated federal efforts to address persistent hazardous exposures to lead. Am J Public Health. 2022;112:S640–6. https://doi.org/10.2105/ajph.2022.306972 .
doi: 10.2105/ajph.2022.306972
pubmed: 36179299
pmcid: 9528644
President’s Task Force on Environmental Health Risks and Safety Risks to Children. Federal Action Plan to Reduce Childhood Lead Exposures and Associated Health Impacts, 2018. https://www.epa.gov/lead/federal-action-plan-reduce-childhood-lead-exposure . Accessed 2 February 2023.
US Environmental Protection Agency (EPA). EPA Strategy to Reduce Lead Exposures and Disparities in U.S. Communities, 2022. https://www.epa.gov/lead/final-strategy-reduce-lead-exposures-and-disparities-us-communities . Accessed 2 February 2023.
Zartarian V, Poulakos A, Garrison VH, Spalt N, Tornero-Velez R, Xue J, et al. Lead data mapping to prioritize US locations for whole-of-government exposure prevention efforts: state of the science, federal collaborations, and remaining challenges. Am J Public Health. 2022;112:S658–69. https://doi.org/10.2105/AJPH.2022.307051 .
doi: 10.2105/AJPH.2022.307051
pubmed: 36179290
pmcid: 9528653
Xue J, Zartarian V, Tornero-Velez R, Stanek LW, Poulakos A, Walts A, et al. A generalizable evaluated approach, applying advanced geospatial statistical methods, to identify high lead exposure locations at census tract scale: michigan case study. Environ Health Perspect. 2022;130:77004. https://doi.org/10.1289/EHP9705 .
doi: 10.1289/EHP9705
pubmed: 35894594
Roberts EM, Madrigal D, Valle J, King G, Kite L. Assessing child lead poisoning case ascertainment in the US, 1999-2010. Pediatrics. 2017;139:10. https://doi.org/10.1542/peds.2016-4266 .
doi: 10.1542/peds.2016-4266
Ohio Housing Finance Authority (OHFA). Fiscal Year 2021 Ohio Housing Needs Assessment, 2022. https://ohiohome.org/research/housingneeds.aspx .
Ohio Department of Health (ODH) and Ohio Health Homes and Lead Poisoining Prevention Program (OHHLPP). Final Report on Targeted Testing Plan for Childhood Lead Poisioning. April 2013.
Ohio Department of Health (ODH). Personal communication. 2023a. 14 April 2023.
Ord JK, Getis A. Local spatial autocorrelation statistics: distributional issues and an application. Geogr Anal. 1995;27:286–306.
Census Bureau. 2010. 2010 Decennial Census. https://data.census.gov/cedsci/all?g=0100000US%241400000&y=2010&d=DEC%20Summary%20File%201 [accessed 16 June]. 2022.
US Environmental Protection Agency (EPA). EJSREEN Technical Documentation, Washington, D.C., 2019. https://www.epa.gov/sites/default/files/2017-09/documents/2017_ejscreen_technical_document.pdf . Accessed 23 January 2023.
Census Bureau. 2011–2015 American Commnity Survey 5-year estimates. 2015. https://data.census.gov/cedsci/all?y=2015&d=ACS%205-Year%20Estimates%20Detailed%20Tables . Accessed 5 May 2023.
Schultz BD, Morara M, Buxton BE, Weintraub M. Predicting blood-lead levels among U.S. children at the census tract level. Environ Justice. 2017;10:129–36. https://doi.org/10.1089/env.2017.0005 .
doi: 10.1089/env.2017.0005
Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159–74.
doi: 10.2307/2529310
pubmed: 843571
Garrison VEH, Ashley PJ. Identifying jurisdictions at risk of containing housing units with deteriorated paint: results and targeting implications for the US Department of Housing and Urban Development. J Public Health Manag Pract. 2021;27:546–57. https://doi.org/10.1097/PHH.0000000000001191 .
doi: 10.1097/PHH.0000000000001191
pubmed: 32658085
Ohio Department of Health (ODH). Number of Ohio Children, Less Than Six Years of Age, Tested for Lead (1999–2021). 2023b. https://odh.ohio.gov/know-our-programs/childhood-lead-poisoning/data-and-statistics/number-of-children-tested . Accessed 5 April 2023.
Ohio Department of Health (ODH). Prevalence of Confirmed Elevated Blood Lead Levels Among Tested Ohio Children. 2023c. https://odh.ohio.gov/know-our-programs/childhood-lead-poisoning/data-and-statistics/prevalence-of-confirmed-elevated-blood-lead-levels . Accessed 5 April 2023.
Obrycki JF, Serafini T, Hood DB, Alexander C, Blais P, Basta NT. Using public health data for soil Pb hazard management in Ohio. J Public Health Manag Pr. 2018;24:E18–E24.
Ohio Department of Health (ODH). Blood Lead Testing Requirements For Ohio Children less than 6 Years of Age. Ohio Healthy Homes and Lead Poisoning Prevention Program, 2018. https://odh.ohio.gov/know-our-programs/childhood-lead-poisoning/for-healthcare-providers/lead-testing-requirements-and-zip-codes . Accessed 31 January 2023.
Litaker D, Kippes CM, Gallagher TE, O’Connor ME. Targeting lead screening: the Ohio lead risk score. Pediatrics. 2000;106:E69. https://doi.org/10.1542/peds.106.5.e69 .
doi: 10.1542/peds.106.5.e69
pubmed: 11061806
Cornwell DA, Brown RA, Via SH. National survey of lead service line occurrence. J Am Water Works Assoc. 2016;108:E182–91. https://doi.org/10.5942/jawwa.2016.108.0086 .
doi: 10.5942/jawwa.2016.108.0086
Stewart LR, Farver JR, Gorsevski PV, Miner JG. Spatial prediction of blood lead levels in children in Toledo, OH using fuzzy sets and the site-specific IEUBK model. J. Appl Geochem. 2014;45:120–9. https://doi.org/10.1016/j.apgeochem.2014.03.012 .
doi: 10.1016/j.apgeochem.2014.03.012
Frank JJ, Poulakos AG, Tornero-Velez R, Xue J. Systematic review and meta-analyses of lead (Pb) concentrations in environmental media (soil, dust, water, food, and air) reported in the United States from 1996 to 2016. Sci Total Environ. 2019;694:133489. https://doi.org/10.1016/j.scitotenv.2019.07.295 .
doi: 10.1016/j.scitotenv.2019.07.295
pubmed: 31756826
pmcid: 6918466
Laidlaw MA, Filippelli G, Mielke H, Gulson B, Ball AS. Lead exposure at firing ranges-a review. Environ Health. 2017;16:34. https://doi.org/10.1186/s12940-017-0246-0 .
doi: 10.1186/s12940-017-0246-0
pubmed: 28376827
pmcid: 5379568
Shakya S, Bhatta MP. Elevated blood lead levels among resettled refugee children in Ohio, 2009-2016. Am J Public Health. 2019;109:912–20. https://doi.org/10.2105/ajph.2019.305022 .
doi: 10.2105/ajph.2019.305022
pubmed: 30998405
pmcid: 6507970
Zartarian VG, Xue J, Poulakos AG, Tornero-Velez R, Stanek LW, Snyder E, et al. A U.S. lead exposure hotspots analysis. Environ Sci Technol. 2024;58:3311. https://doi.org/10.1021/acs.est.3c07881
doi: 10.1021/acs.est.3c07881
pubmed: 38334298
pmcid: 10882963
Office of the Governor, State of Ohio. Recommendations of the Governor’s Lead Advisory Committee, 2021. https://governor.ohio.gov/media/news-and-media/lead-advisory-committee-final-report-01302021 . Accessed 6 January 2023.