Retrograde Cricopharyngeus Dysfunction, a New Motility Disorder: Single Center Case Series and Treatment Results.

Botulinum toxins Esophageal sphincter, upper Manometry

Journal

Journal of neurogastroenterology and motility
ISSN: 2093-0879
Titre abrégé: J Neurogastroenterol Motil
Pays: Korea (South)
ID NLM: 101530189

Informations de publication

Date de publication:
30 Apr 2024
Historique:
received: 06 07 2023
revised: 15 08 2023
accepted: 01 09 2023
medline: 5 4 2024
pubmed: 5 4 2024
entrez: 5 4 2024
Statut: ppublish

Résumé

Retrograde cricopharyngeus dysfunction (R-CPD) is a new clinical entity characterized by inability to belch and associated symptoms of loud gurgling noises, chest and/or abdominal pressure, abdominal bloating, and excessive flatulence. R-CPD can be treated with botulinum toxin (BT) injection in the upper esophageal sphincter. We hereby report patient demographics, symptomatology, and treatment results of a series of consecutive patients who presented at our center. Data on 50 consecutive patients presenting with R-CPD were prospectively collected using a standardized questionnaire prior to, 1 month after treatment and at the end of follow-up. All patients were diagnosed using a set of clinical symptoms. Fifty patients (26 females) were included, median age was 27.5 years (range, 17-65). Median body mass index was 22.7 kg/m Our case series of 50 patients with R-CPD shows very good short-term and good long-term improvement of symptoms after injection of BT. These results are in line with previous studies.

Sections du résumé

Background/Aims UNASSIGNED
Retrograde cricopharyngeus dysfunction (R-CPD) is a new clinical entity characterized by inability to belch and associated symptoms of loud gurgling noises, chest and/or abdominal pressure, abdominal bloating, and excessive flatulence. R-CPD can be treated with botulinum toxin (BT) injection in the upper esophageal sphincter. We hereby report patient demographics, symptomatology, and treatment results of a series of consecutive patients who presented at our center.
Methods UNASSIGNED
Data on 50 consecutive patients presenting with R-CPD were prospectively collected using a standardized questionnaire prior to, 1 month after treatment and at the end of follow-up. All patients were diagnosed using a set of clinical symptoms.
Results UNASSIGNED
Fifty patients (26 females) were included, median age was 27.5 years (range, 17-65). Median body mass index was 22.7 kg/m
Conclusions UNASSIGNED
Our case series of 50 patients with R-CPD shows very good short-term and good long-term improvement of symptoms after injection of BT. These results are in line with previous studies.

Identifiants

pubmed: 38576368
pii: jnm23099
doi: 10.5056/jnm23099
doi:

Types de publication

Journal Article

Langues

eng

Pagination

177-183

Auteurs

Stijn Arnaert (S)

Department of Gastroenterology, AZ Delta, Roeselare, Belgium.

Joris Arts (J)

Department of Gastroenterology, AZ Sint-Lucas, Brugge, Belgium.
Department of Gastroenterology, UZ Leuven, Leuven, Belgium.

Karlien Raymenants (K)

Department of Gastroenterology, UZ Leuven, Leuven, Belgium.

Filip Baert (F)

Department of Gastroenterology, AZ Delta, Roeselare, Belgium.

Kathelijne Delsupehe (K)

Department of Otolaryngology, Head and Neck Surgery, AZ Delta, Roeselare, Belgium.

Classifications MeSH