Asthma management, focused on the use of oral corticosteroids: the opinions of Italian asthmatic patients.


Journal

The Journal of asthma : official journal of the Association for the Care of Asthma
ISSN: 1532-4303
Titre abrégé: J Asthma
Pays: England
ID NLM: 8106454

Informations de publication

Date de publication:
05 Apr 2024
Historique:
medline: 5 4 2024
pubmed: 5 4 2024
entrez: 5 4 2024
Statut: aheadofprint

Résumé

Patients' perceptions of asthma symptoms, and attitudes regarding diagnosis and management, can affect their ability to reach good asthma control. The aim of the study was to explore patients' perceptions of asthma management, with focus on treatment with oral corticosteroids (OCS). A DOXAPHARMA survey was conducted. A questionnaire with 46 multiple choice questions was completed by 50 patients with severe uncontrolled asthma, and 258 with mild-moderate controlled or partly controlled asthma. Participants were representative of Italian asthmatic patients-with medium age, long asthma duration, delayed diagnosis, poor asthma control, and frequent exacerbations. Many asthmatics reported inadequate pharmacologic treatment. The majority but not all patients regularly used ICS/LABA. Oral treatment was common, mainly with OCS, particularly in severe asthmatics. One-fourth of patients did not regularly use inhaled therapy, and adherence was poor, resulting in frequent OCS use to treat exacerbations, which were common in mild-moderate cases. Patients were fairly satisfied with asthma therapies, but many had concerns about long-term corticosteroid use. Patients complained about poor management of comorbidities associated with asthma and OCS use, but were generally satisfied with their patient/doctor relationships. Many patients failed to achieve optimal health-related quality of life (HRQoL), mainly those with severe asthma who used OCS treatment and emphasized how OCS therapy impacted QoL. The survey results confirmed many problems related to mild-moderate and severe asthma management in Italy and highlighted the overuse of OCS rather than more effective and safe treatments, which had strong negative effects on HRQoL.

Identifiants

pubmed: 38578082
doi: 10.1080/02770903.2024.2338863
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-26

Auteurs

Manuela Latorre (M)

Pulmonology Unit, Department of Medical Specialties, Nuovo Ospedale Apuano, Massa, Italy.

Angela Rizzi (A)

UOSD Allergologia e Immunologia Clinica, Dipartimento Scienze Mediche e Chirurgiche addominali ed endocrino metaboliche, Roma, Italy.

Pierluigi Paggiaro (P)

Department of Surgery, Medicine, Molecular Biology and Critical Care, University of Pisa, Pisa, Italy.

Ilaria Baiardini (I)

Respiratory Clinic, Department of Internal Medicine, University of Genoa, Genoa, Italy.

Diego Bagnasco (D)

Clinica delle Malattie Respiratorie ed Allergologia, IRCCS Policlinico San Martino, Genova, Italy.
Dipartimento di Medicina Interna (DIMI), Università degli Studi di Genova, Italy.

Stefano DelGiacco (S)

Unit of Allergy and Clinical Immunology, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

Carlo Lombardi (C)

Departmental Unit of Allergology & Respiratory Diseases Fondazione Poliambulanza Brescia, Italy.

Vincenzo Patella (V)

Department of Internal and Respiratory Medicine, Division of Allergy and Clinical Immunology, "Santa Maria della Speranza" Hospital, Salerno, Italy.

Eleonora Nucera (E)

UOSD Allergologia e Immunologia Clinica, Dipartimento Scienze Mediche e Chirurgiche addominali ed endocrino metaboliche, Roma, Italy.
Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.

Roberta Parente (R)

Division of Allergy and Clinical Immunology, Department of Medicine, University of Salerno, Italy.

Giovanni Paoletti (G)

Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Personalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy.

Laura Pini (L)

Department of Clinical and Experimental Sciences, Spedali Civili di Brescia, University of Brescia, Italy.

Erminia Ridolo (E)

Department of Medicine and Surgery, University of Parma, Parma, Italy.

Gianenrico Senna (G)

Asthma Center and Allergy Unit, University of Verona and General Hospital, Verona, Italy.

Francesco Blasi (F)

Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Center, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

Giorgio Walter Canonica (GW)

Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Personalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy.

Arianna Aruanno (A)

UOSD Allergologia e Immunologia Clinica, Dipartimento Scienze Mediche e Chirurgiche addominali ed endocrino metaboliche, Roma, Italy.

Carmen Ballacchino (C)

APACS APS - Associazione Pazienti della Sindrome di Churg Strauss.

Marco Bonavia (M)

Respiratory Rehabilitation, ASL3, Genoa, Italy.

Cecilia Calabrese (C)

Department of Translational Medical Sciences, University of Campania "L. Vanvitelli", Naples, Italy.

Marco Caminati (M)

Department of Medicine, Asthma, Allergy and Clinical Immunology Section, University of Verona, Verona, Italy.

Monica Carbonara (M)

FederASMA e ALLERGIE OdV - Federazione Italiana Pazienti.

Cristina Cardini (C)

Fondazione della Salute Respiratoria della Società Itaiana di Pneumologia SIP-IRS (via San Gregorio 12, 20124, Milano) Milan, Italy.

Cristiano Caruso (C)

UOSD DH INTERNAL MEDICINE AND DIGESTIVE DISEASE, Fondazione Policlinico A. Gemelli, IRCCS Rome Italy.

Luciano Cattani (L)

FederASMA e ALLERGIE OdV - Federazione Italiana Pazienti.
AsmaGrave OdV.

Maria Angiola Crivellaro (MA)

Occupational Health Unit and Allergology Padova University Hospital, Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Padova, Italy.

Alessandra Diana (A)

APACS APS - Associazione Pazienti della Sindrome di Churg Strauss.

Eugenia Durante (E)

APACS APS - Associazione Pazienti della Sindrome di Churg Strauss.

Elisabetta Favero (E)

Centro Allergologico e Malattie Rare, Dipartimento di Medicina Ospedale Ca' Foncello, Treviso, Italy.

Maria Pia Foschino Barbaro (MPF)

Department of Medical and Surgical Sciences, University of Foggia, Italy.

Sandra Frateiacci (S)

FederASMA e ALLERGIE OdV - Federazione Italiana Pazienti.
ALAMA APS - Associazione Liberi dall'Asma, dalle Malattie Allergiche, Atopiche, Respiratorie e Rare.

Gabriella Guarnieri (G)

Department of Cardiac-Thoracic-Vascular Sciences and Public Health, Respiratory Pathophysiology Unit, University of Padova, Padova, Italy.

Alessia Lofaro (A)

FederASMA e ALLERGIE OdV - Federazione Italiana Pazienti.

Francesca Losa (F)

UO di Allergologia, Immunologia clinica e Reumatologia, Ospedale Carlo Poma, ASST Mantova, Italy.

Nadia Magarò (N)

FederASMA e ALLERGIE OdV - Federazione Italiana Pazienti.

Francesco Menzella (F)

Pulmonology Unit, S. Valentino Hospital, AULSS 2 Marca Trevigiana, Montebelluna, Treviso, Italy.

Luisa Ricciardi (L)

Allergy and Clinical Immunology Unit, A.O.U. Policlinico "G. Martino"; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.

Giulia Scioscia (G)

Department of Medical and Surgical Sciences, University of Foggia, Italy.

Elisa Testino (E)

Clinica delle Malattie Respiratorie ed Allergologia, IRCCS Policlinico San Martino, Genova, Italy.

Francesca Torracca (F)

APACS APS - Associazione Pazienti della Sindrome di Churg Strauss.

Classifications MeSH