Measuring Connexin Hemichannel Opening in Response to an InsP3-Mediated Cytosolic Ca
Connexin 32
Gating by cytosolic Ca2+
HeLa cells
Hemichannel conductance
Patch-clamp
Journal
Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969
Informations de publication
Date de publication:
2024
2024
Historique:
medline:
5
4
2024
pubmed:
5
4
2024
entrez:
5
4
2024
Statut:
ppublish
Résumé
The opening of connexin hemichannels (HCs) expressed at the plasma membrane of mammalian cells is regulated by a number of physiological parameters, including extracellular and intracellular Ca
Identifiants
pubmed: 38578422
doi: 10.1007/978-1-0716-3842-2_14
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
189-197Informations de copyright
© 2024. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.
Références
Delmar M et al (2018) Connexins and disease. Cold Spring Harb Perspect Biol 10(9)
Harris AL (2007) Connexin channel permeability to cytoplasmic molecules. Prog Biophys Mol Biol 94(1–2):120–143
doi: 10.1016/j.pbiomolbio.2007.03.011
pubmed: 17470375
pmcid: 1995164
Alexander DB, Goldberg GS (2003) Transfer of biologically important molecules between cells through gap junction channels. Curr Med Chem 10(19):2045–2058
doi: 10.2174/0929867033456927
pubmed: 12871102
Cotrina ML et al (1998) Connexins regulate calcium signaling by controlling ATP release. Proc Natl Acad Sci USA 95(26):15735–15740
doi: 10.1073/pnas.95.26.15735
pubmed: 9861039
pmcid: 28113
Valiunas V (2013) Cyclic nucleotide permeability through unopposed connexin hemichannels. Front Pharmacol 4:75
doi: 10.3389/fphar.2013.00075
pubmed: 23760880
pmcid: 3674318
Ye ZC et al (2003) Functional hemichannels in astrocytes: a novel mechanism of glutamate release. J Neurosci 23(9):3588–3596
doi: 10.1523/JNEUROSCI.23-09-03588.2003
pubmed: 12736329
pmcid: 6742182
Takeuchi H et al (2006) Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner. J Biol Chem 281(30):21362–21368
doi: 10.1074/jbc.M600504200
pubmed: 16720574
Bruzzone S et al (2001) Connexin 43 hemi channels mediate Ca2+−regulated transmembrane NAD+ fluxes in intact cells. FASEB J 15(1):10–12
doi: 10.1096/fj.00-0566fje
pubmed: 11099492
Zocchi E et al (2001) Paracrinally stimulated expansion of early human hemopoietic progenitors by stroma-generated cyclic ADP-ribose. FASEB J 15(9):1610–1612
doi: 10.1096/fj.00-0803fje
pubmed: 11427502
Rana S, Dringen R (2007) Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes. Neurosci Lett 415(1):45–48
doi: 10.1016/j.neulet.2006.12.043
pubmed: 17222973
Orellana JA, Stehberg J (2014) Hemichannels: new roles in astroglial function. Front Physiol 5:193
doi: 10.3389/fphys.2014.00193
pubmed: 24987373
pmcid: 4060415
Meunier C et al (2017) Contribution of Astroglial Cx43 Hemichannels to the modulation of glutamatergic currents by D-serine in the mouse prefrontal cortex. J Neurosci 37(37):9064–9075
doi: 10.1523/JNEUROSCI.2204-16.2017
pubmed: 28821660
pmcid: 6596802
Cherian PP et al (2005) Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin. Mol Biol Cell 16(7):3100–3106
doi: 10.1091/mbc.e04-10-0912
pubmed: 15843434
pmcid: 1165395
Burra S, Jiang JX (2009) Connexin 43 hemichannel opening associated with prostaglandin E(2) release is adaptively regulated by mechanical stimulation. Commun Integr Biol 2(3):239–240
doi: 10.4161/cib.2.3.8154
pubmed: 19641742
pmcid: 2717532
Contreras JE et al (2003) Gating and regulation of connexin 43 (Cx43) hemichannels. Proc Natl Acad Sci USA 100(20):11388–11393
doi: 10.1073/pnas.1434298100
pubmed: 13130072
pmcid: 208767
Valiunas V, Weingart R (2000) Electrical properties of gap junction hemichannels identified in transfected HeLa cells. Pflugers Arch 440(3):366–379
doi: 10.1007/s004240000294
pubmed: 10954323
Gomez-Hernandez JM et al (2003) Molecular basis of calcium regulation in connexin-32 hemichannels. Proc Natl Acad Sci USA 100(26):16030–16035
doi: 10.1073/pnas.2530348100
pubmed: 14663144
pmcid: 307687
Lopez W et al (2016) Mechanism of gating by calcium in connexin hemichannels. Proc Natl Acad Sci USA 113:E7986
doi: 10.1073/pnas.1609378113
pubmed: 27872296
pmcid: 5150374
Carrer A et al (2018) Cx32 hemichannel opening by cytosolic Ca2+ is inhibited by the R220X mutation that causes Charcot-Marie-tooth disease. Hum Mol Genet 27(1):80–94
doi: 10.1093/hmg/ddx386
pubmed: 29077882
De Vuyst E et al (2006) Intracellular calcium changes trigger connexin 32 hemichannel opening. EMBO J 25(1):34–44
doi: 10.1038/sj.emboj.7600908
pubmed: 16341088
De Vuyst E et al (2009) Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cells. Cell Calcium 46(3):176–187
doi: 10.1016/j.ceca.2009.07.002
pubmed: 19656565
Kleopa KA, Abrams CK, Scherer SS (2012) How do mutations in GJB1 cause X-linked Charcot-Marie-tooth disease? Brain Res 1487:198–205
doi: 10.1016/j.brainres.2012.03.068
pubmed: 22771394
pmcid: 3488165
Meier C et al (2004) Connexin32-containing gap junctions in Schwann cells at the internodal zone of partial myelin compaction and in Schmidt-Lanterman incisures. J Neurosci 24(13):3186–3198
doi: 10.1523/JNEUROSCI.5146-03.2004
pubmed: 15056698
pmcid: 1803337
Balice-Gordon RJ, Bone LJ, Scherer SS (1998) Functional gap junctions in the schwann cell myelin sheath. J Cell Biol 142(4):1095–1104
doi: 10.1083/jcb.142.4.1095
pubmed: 9722620
pmcid: 2132877
Nualart-Marti A et al (2013) Role of connexin 32 hemichannels in the release of ATP from peripheral nerves. Glia 61(12):1976–1989
doi: 10.1002/glia.22568
pubmed: 24123415
Lev-Ram V, Ellisman MH (1995) Axonal activation-induced calcium transients in myelinating Schwann cells, sources, and mechanisms. J Neurosci 15(4):2628–2637
doi: 10.1523/JNEUROSCI.15-04-02628.1995
pubmed: 7722618
pmcid: 6577779
Mayer C et al (1997) Intracellular calcium transients mediated by P2 receptors in the paranodal Schwann cell region of myelinated rat spinal root axons. Neurosci Lett 224(1):49–52
doi: 10.1016/S0304-3940(97)13457-7
pubmed: 9132688
Stevens B, Fields RD (2000) Response of Schwann cells to action potentials in development. Science 287(5461):2267–2271
doi: 10.1126/science.287.5461.2267
pubmed: 10731149
Ino D et al (2015) Neuronal regulation of Schwann cell mitochondrial Ca(2+) signaling during myelination. Cell Rep 12(12):1951–1959
doi: 10.1016/j.celrep.2015.08.039
pubmed: 26365190