Paediatric hepatic angiosarcoma with consumptive hypothyroidism-an important diagnostic pitfall to avoid during evaluation of hepatic vascular tumours.
Angiosarcoma
Children
Haemangioma
Hypothyroidism
Liver
Magnetic resonance imaging
Journal
Pediatric radiology
ISSN: 1432-1998
Titre abrégé: Pediatr Radiol
Pays: Germany
ID NLM: 0365332
Informations de publication
Date de publication:
06 Apr 2024
06 Apr 2024
Historique:
received:
29
01
2024
accepted:
20
03
2024
revised:
18
03
2024
medline:
6
4
2024
pubmed:
6
4
2024
entrez:
5
4
2024
Statut:
aheadofprint
Résumé
Hepatic angiosarcoma is an extremely rare primary malignant vascular tumour in children with very poor prognosis. Radiological diagnosis of hepatic angiosarcoma is challenging due to overlapping imaging features with other benign vascular hepatic tumours, particularly infantile hepatic haemangioma. Consumptive hypothyroidism is a condition that is almost exclusively associated with infantile hepatic haemangioma and has never been reported in angiosarcoma. We present a case of hepatic angiosarcoma in a 20-month-old girl, associated with consumptive hypothyroidism and, as a result, initially misdiagnosed as infantile hepatic haemangioma. Radiologists should be aware that consumptive hypothyroidism is not a reliable feature to use in excluding paediatric hepatic angiosarcoma. Biopsy should be performed in patients older than 1 year of age or with atypical imaging features.
Identifiants
pubmed: 38580747
doi: 10.1007/s00247-024-05915-7
pii: 10.1007/s00247-024-05915-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
Grassia KL, Peterman CM, Iacobas I et al (2017) Clinical case series of pediatric hepatic angiosarcoma. Pediatr Blood Cancer 64:e26627. https://doi.org/10.1002/pbc.26627
doi: 10.1002/pbc.26627
McGuire A, Fernandez-Pineda I, Fishman SJ, Dickie BH (2020) Pediatric hepatic vascular tumors. Semin Pediatr Surg 29:150970. https://doi.org/10.1016/j.sempedsurg.2020.150970
doi: 10.1016/j.sempedsurg.2020.150970
pubmed: 33069290
Huang SA, Tu HM, Harney JW et al (2000) Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. N Engl J Med 343:185–189. https://doi.org/10.1056/NEJM200007203430305
doi: 10.1056/NEJM200007203430305
pubmed: 10900278
Pickhardt PJ, Kitchin D, Lubner MG et al (2015) Primary hepatic angiosarcoma: multi-institutional comprehensive cancer centre review of multiphasic CT and MR imaging in 35 patients. Eur Radiol 25:315–322. https://doi.org/10.1007/s00330-014-3442-0
doi: 10.1007/s00330-014-3442-0
pubmed: 25278246
Bruegel M, Muenzel D, Waldt S et al (2013) Hepatic angiosarcoma: cross-sectional imaging findings in seven patients with emphasis on dynamic contrast-enhanced and diffusion-weighted MRI. Abdom Imaging 38:745–754. https://doi.org/10.1007/s00261-012-9967-2
doi: 10.1007/s00261-012-9967-2
pubmed: 23223833
Drinković I, Brkljacić B (1996) Two cases of lethal complications following ultrasound-guided percutaneous fine-needle biopsy of the liver. Cardiovasc Intervent Radiol 19:360–363. https://doi.org/10.1007/BF02570192
doi: 10.1007/BF02570192
pubmed: 8781161
Kang TW, Lee MW, Choi D et al (2016) Safety of percutaneous biopsy for hepatic angiosarcoma: results of a multicenter Korean survey. J Vasc Interv Radiol 27:846–851. https://doi.org/10.1016/j.jvir.2016.01.148
doi: 10.1016/j.jvir.2016.01.148
pubmed: 27080009
Ackermann O, Fabre M, Franchi S et al (2011) Widening spectrum of liver angiosarcoma in children. J Pediatr Gastroenterol Nutr 53:615–619. https://doi.org/10.1097/MPG.0b013e318230146c
doi: 10.1097/MPG.0b013e318230146c
pubmed: 21832953