Outcome of right ventricular microaxial pump support in patients undergoing cardiac surgery.

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
06 Apr 2024
Historique:
received: 12 06 2023
accepted: 01 04 2024
medline: 6 4 2024
pubmed: 6 4 2024
entrez: 5 4 2024
Statut: epublish

Résumé

Right ventricular failure (RVF) after cardiac surgery is associated with an in-hospital mortality rate of up to 75%. Microaxial flow pumps are one of the mechanical circulatory supports (MCS) options available for the treatment of RVF, however the specifics of timing and indication for MCS, as well as predictors for survival, remain unclear due to a dearth of published data. We evaluated the clinical outcome of patients treated with Impella-RP for predictors of mortality and the hemodynamic effects of the pump. This is a single-center retrospective observational study involving adult patients who underwent cardiac surgery with cardiopulmonary bypass between January 2019 and December 2020 in cardiac surgery and required therapeutic management of RVF with an Impella-RP. Overall, 18 patients were included and analyzed for factors that could be associated with mortality, or that could be predictors of patient outcomes for this population. Treatment of RVF with Impella-RP improved the patient hemodynamics significantly and had a survival rate of 61% within 30 days. Patients with isolated CABG or better liver function before implantation had a better survival rate, which may indicate that underlying disease and timing of implantation are significant for successful treatment of RVF.

Identifiants

DOI: 10.1038/s41598-024-58602-w PMID: 38580761
pubmed: 38580761
doi: 10.1038/s41598-024-58602-w
pii: 10.1038/s41598-024-58602-w
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

8078

Informations de copyright

© 2024. The Author(s).

Références

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Auteurs

Medina Marta (M)

Department of Cardiovasular Surgery, University Hospital of Mainz, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.

Mahmoud Zada (M)

Department of Cardiology and Rhythmology, Hospital Mechernich, Mechernich, Germany.

Nils Theuerkauf (N)

Department of Anesthesiology and Intensive Care Medicine, University Hospital of Bonn, Bonn, Germany.

Georg Daniel Duerr (GD)

Department of Cardiovasular Surgery, University Hospital of Mainz, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.

Sebastian Zimmer (S)

Department of Cardiology, University Hospital of Bonn, Bonn, Germany.

Hendrik Treede (H)

Department of Cardiovasular Surgery, University Hospital of Mainz, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.

Mehmet Oezkur (M)

Department of Cardiovasular Surgery, University Hospital of Mainz, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany. m.oezkur@gmail.com.

Classifications MeSH