Unmet needs and barriers in venous thromboembolism education and awareness among people living with cancer: A global survey.

Journal

Journal of thrombosis and haemostasis : JTH
ISSN: 1538-7836
Titre abrégé: J Thromb Haemost
Pays: England
ID NLM: 101170508

Informations de publication

Date de publication:
04 Apr 2024
Historique:
received: 20 11 2023
revised: 02 03 2024
accepted: 21 03 2024
medline: 7 4 2024
pubmed: 7 4 2024
entrez: 6 4 2024
Statut: aheadofprint

Résumé

Venous thromboembolism (VTE) is a major preventable cause of morbidity, disability, and mortality in subjects with cancer. A global appraisal of cancer-associated VTE education and awareness is not available. To evaluate VTE-related education, awareness, and unmet needs from the perspective of people living with cancer using a quantitative and qualitative approach. This cross-sectional study used data from an online-based survey covering multidimensional domains of cancer-associated VTE. Data are presented descriptively. Potential differences across participant subgroups were explored. Among 2262 patients with cancer from 42 countries worldwide, 55.3% received no VTE education throughout their cancer journey, and an additional 8.2% at the time of VTE diagnosis only, leading to 63.5% receiving none or inappropriately delayed education. When education was delivered, only 67.8% received instructions to seek medical attention in case of VTE suspicion, and 36.9% reported scarce understanding. One third of participants (32.4%) felt psychologically distressed when becoming aware of the potential risks and implications connected with cancer-associated VTE. Most responders (78.8%) deemed VTE awareness highly relevant, but almost half expressed concerns on the quality of education received. While overall consistent, findings in selected survey domains appeared to numerically differ across age groups, ethnicity, continent of residence, educational level, metastatic status, and VTE history. This study involving a large and diverse population of individuals living with cancer identifies important unmet needs in VTE-related education, awareness, and support across healthcare systems globally. These findings unveil multilevel opportunities to expedite patient-centered care in cancer-associated VTE prevention and management.

Sections du résumé

BACKGROUND BACKGROUND
Venous thromboembolism (VTE) is a major preventable cause of morbidity, disability, and mortality in subjects with cancer. A global appraisal of cancer-associated VTE education and awareness is not available.
OBJECTIVES OBJECTIVE
To evaluate VTE-related education, awareness, and unmet needs from the perspective of people living with cancer using a quantitative and qualitative approach.
PATIENTS/METHODS METHODS
This cross-sectional study used data from an online-based survey covering multidimensional domains of cancer-associated VTE. Data are presented descriptively. Potential differences across participant subgroups were explored.
RESULTS RESULTS
Among 2262 patients with cancer from 42 countries worldwide, 55.3% received no VTE education throughout their cancer journey, and an additional 8.2% at the time of VTE diagnosis only, leading to 63.5% receiving none or inappropriately delayed education. When education was delivered, only 67.8% received instructions to seek medical attention in case of VTE suspicion, and 36.9% reported scarce understanding. One third of participants (32.4%) felt psychologically distressed when becoming aware of the potential risks and implications connected with cancer-associated VTE. Most responders (78.8%) deemed VTE awareness highly relevant, but almost half expressed concerns on the quality of education received. While overall consistent, findings in selected survey domains appeared to numerically differ across age groups, ethnicity, continent of residence, educational level, metastatic status, and VTE history.
CONCLUSIONS CONCLUSIONS
This study involving a large and diverse population of individuals living with cancer identifies important unmet needs in VTE-related education, awareness, and support across healthcare systems globally. These findings unveil multilevel opportunities to expedite patient-centered care in cancer-associated VTE prevention and management.

Identifiants

DOI: 10.1016/j.jtha.2024.03.019 PMID: 38582384
pubmed: 38582384
pii: S1538-7836(24)00177-6
doi: 10.1016/j.jtha.2024.03.019
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Investigateurs

Cihan Ay (C)
Marc Carrier (M)
Pichika Chantrathammachart (P)
Jean M Connors (JM)
Erich V De Paula (EV)
Mert Dumantepe (M)
Ioannis T Farmakis (IT)
George Giannakoulas (G)
Shinya Goto (S)
Maria C Guillermo Esposito (MC)
Florent Happe (F)
Beverley J Hunt (BJ)
Luis Jara-Palomares (L)
Zhi-Cheng Jing (ZC)
Lai Heng Lee (LH)
Gordon McPherson (G)
Eriko Morishita (E)
Todd Robertson (T)
Charles M Samama (CM)
Maria de Jèsus Uribe Dominguez (M)
Tzu-Fei Wang (TF)

Informations de copyright

Copyright © 2024 International Society on Thrombosis and Haemostasis. Published by Elsevier Inc. All rights reserved.

Auteurs

Nicola Potere (N)

Department of Medicine and Ageing Sciences, School of Medicine and Health Sciences, "G. D'Annunzio" University, Chieti, Italy. Electronic address: nic.potere@gmail.com.

Isabelle Mahé (I)

Université Paris Cité, Assistance Publique des Hôpitaux de Paris, Hôpital Louis Mourier, Paris, France; Innovative Therapies in Haemostasis, INSERM UMR_S1140, INNOVTE-FRIN, France.

Pantep Angchaisuksiri (P)

Division of Hematology, Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Gabriela Cesarman-Maus (G)

Department of Hematology, Instituto Nacional de Cancerología, Mexico City, Mexico.

Chee Wee Tan (CW)

Department of Hematology, Royal Adelaide Hospital, Adelaide, Australia; University of Adelaide, South Australia, Australia.

Anila Rashid (A)

Section of Haematology, Department of Pathology & Laboratory Medicine/Oncology, Aga Khan University Hospital, Pakistan.

Farjah H AlGahtani (FH)

Division of Hematology-Oncology, Oncology Center, Department of Medicine, King Saud University, Riyadh, Saudi Arabia.

Egidio Imbalzano (E)

Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.

Nick van Es (N)

Amsterdam UMC location University of Amsterdam, Department of Vascular Medicine, Meibergdreef 9, Amsterdam, The Netherlands; Amsterdam Cardiovascular Sciences, Pulmonary Hypertension & Thrombosis, Amsterdam, The Netherlands.

Avi Leader (A)

Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah Tikva; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Medicine, Hematology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Edeghonghon Olayemi (E)

Department of Hematology, University of Ghana Medical School, Accra, Ghana.

Ettore Porreca (E)

Department of Innovative Technologies in Medicine and Dentistry, School of Medicine and Health Sciences, "G. D'Annunzio" University, Chieti, Italy.

Fionnuala Ní Áinle (FN)

Department of Hematology, Mater Misericordiae University Hospital and Rotunda Hospital, Dublin, Ireland; School of Medicine, University College, Dublin, Ireland.

Helen C Okoye (HC)

Department of Hematology and Immunology, College of Medicine, University of Nigeria, Enugu, Nigeria.

Matteo Candeloro (M)

Department of Innovative Technologies in Medicine and Dentistry, School of Medicine and Health Sciences, "G. D'Annunzio" University, Chieti, Italy.

Didier Mayeur (D)

Medical Oncology, Transversal Department of Supportive Care, Association Francophone des Soins Oncologiques de Support (AFSOS), Centre Georges-François Leclerc, Dijon, France.

Luca Valerio (L)

Center for Thrombosis and Hemostasis, University Hospital Mainz, Germany; Center for Cardiology, University Hospital Mainz, Germany.

R Cary Clark (RC)

Programs and Education, International Society on Thrombosis and Haemostasis, Carrboro, North Carolina, USA.

Lana A Castellucci (LA)

Department of Medicine, Ottawa Hospital Research Institute and University of Ottawa, Ottawa, Ontario, Canada.

Stefano Barco (S)

Center for Thrombosis and Hemostasis, University Hospital Mainz, Germany; Center for Cardiology, University Hospital Mainz, Germany; Department of Angiology, University Hospital Zurich, Zurich, Switzerland.

Marcello Di Nisio (M)

Department of Medicine and Ageing Sciences, School of Medicine and Health Sciences, "G. D'Annunzio" University, Chieti, Italy.

Classifications MeSH