Developmental trajectories of GABAergic cortical interneurons are sequentially modulated by dynamic

cortex development gene-dosage inhibitory neuron interneuron

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
16 Apr 2024
Historique:
medline: 8 4 2024
pubmed: 8 4 2024
entrez: 8 4 2024
Statut: ppublish

Résumé

GABAergic inhibitory interneurons, originating from the embryonic ventral forebrain territories, traverse a convoluted migratory path to reach the neocortex. These interneuron precursors undergo sequential phases of tangential and radial migration before settling into specific laminae during differentiation. Here, we show that the developmental trajectory of

Identifiants

DOI: 10.1073/pnas.2317783121 PMID: 38588430
pubmed: 38588430
doi: 10.1073/pnas.2317783121
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2317783121

Subventions

Organisme : Astellas Foundation for Research on Metabolic Disorders
ID : 2022
Organisme : Masato Kawano Memorial Public Interest Foundation for Promotion of Pediatrics (Masato Kawano Memorial Foundation for Promotion of Pediatrics)
ID : 2022
Organisme : FOXG1 Research Foundation
ID : 2023
Organisme : Takeda Science Foundation (TSF)
ID : 2016
Organisme : Mochida Memorial Foundation for Medical and Pharmaceutical Research ( )
ID : 2016
Organisme : Cell Science Research Foundation
ID : 2017
Organisme : Brain Science Foundation (BSF)
ID : 2016
Organisme : Mitsubishi Foundation (The Mitsubishi Foundation)
ID : 2023
Organisme : MEXT | Japan Society for the Promotion of Science (JSPS)
ID : JP17H05775 JP17K07102 JP19H04789 JP19H05228 JP20K07362 JP23H02683 JP23H04211
Organisme : MEXT | Japan Society for the Promotion of Science (JSPS)
ID : JP15H01667 JP19H03343 JP20H05916
Organisme : HHS | NIH | National Institute of Mental Health (NIMH)
ID : R01MH095147

Déclaration de conflit d'intérêts

Competing interests statement:The authors declare no competing interest.

Auteurs

Goichi Miyoshi (G)

Department of Developmental Genetics and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi city, Gunma 371-8511, Japan.
Department of Neurophysiology, Tokyo Women's Medical University, Shinjuku, Tokyo 162-8666, Japan.
Department of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY 10016.
ORCID: 0000-0002-1872-6278

Yoshifumi Ueta (Y)

Department of Neurophysiology, Tokyo Women's Medical University, Shinjuku, Tokyo 162-8666, Japan.

Yuki Yagasaki (Y)

Department of Neurophysiology, Tokyo Women's Medical University, Shinjuku, Tokyo 162-8666, Japan.

Yusuke Kishi (Y)

Laboratory of Molecular Neurobiology, Institute for Quantitative Biosciences, University of Tokyo, Bunkyo, Tokyo 113-0032, Japan.
Laboratory of Molecular Biology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Bunkyo, Tokyo 113-0033, Japan.
ORCID: 0000-0003-2846-5400

Gord Fishell (G)

Department of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY 10016.
Department of Neurobiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Stanley Center at the Broad Institute, Cambridge, MA 02142.

Robert P Machold (RP)

Department of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY 10016.

Mariko Miyata (M)

Department of Neurophysiology, Tokyo Women's Medical University, Shinjuku, Tokyo 162-8666, Japan.
ORCID: 0000-0001-5688-654X

Classifications MeSH