Continuous glucose monitoring and intrapersonal variability in fasting glucose.


Journal

Nature medicine
ISSN: 1546-170X
Titre abrégé: Nat Med
Pays: United States
ID NLM: 9502015

Informations de publication

Date de publication:
08 Apr 2024
Historique:
received: 19 11 2023
accepted: 04 03 2024
medline: 9 4 2024
pubmed: 9 4 2024
entrez: 8 4 2024
Statut: aheadofprint

Résumé

Plasma fasting glucose (FG) levels play a pivotal role in the diagnosis of prediabetes and diabetes worldwide. Here we investigated FG values using continuous glucose monitoring (CGM) devices in nondiabetic adults aged 40-70 years. FG was measured during 59,565 morning windows of 8,315 individuals (7.16 ± 3.17 days per participant). Mean FG was 96.2 ± 12.87 mg dl

Identifiants

pubmed: 38589602
doi: 10.1038/s41591-024-02908-9
pii: 10.1038/s41591-024-02908-9
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer Nature America, Inc.

Références

Khan, M. A. B. et al. Epidemiology of type 2 diabetes—global burden of disease and forecasted trends. J. Epidemiol. Glob. Health 10, 107–111 (2020).
doi: 10.2991/jegh.k.191028.001 pubmed: 32175717 pmcid: 7310804
Danaei, G. et al. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet 378, 31–40 (2011).
doi: 10.1016/S0140-6736(11)60679-X pubmed: 21705069
American Diabetes Association. Standards of medical care in diabetes—2022 abridged for primary care providers. Clin. Diabetes 40, 10–38 (2022).
Norberg, M. et al. A combination of HbA1c, fasting glucose and BMI is effective in screening for individuals at risk of future type 2 diabetes: OGTT is not needed. J. Intern. Med. 260, 263–271 (2006).
doi: 10.1111/j.1365-2796.2006.01689.x pubmed: 16918824
Rasmussen, S. S. et al. Short-term reproducibility of impaired fasting glycaemia, impaired glucose tolerance and diabetes the ADDITION study, DK. Diabetes Res. Clin. Pract. 80, 146–152 (2008).
doi: 10.1016/j.diabres.2007.11.003 pubmed: 18082284
Mooy, J. M. et al. Intra-individual variation of glucose, specific insulin and proinsulin concentrations measured by two oral glucose tolerance tests in a general Caucasian population: the Hoorn study. Diabetologia 39, 298–305 (1996).
doi: 10.1007/BF00418345 pubmed: 8721775
Brohall, G., Behre, C. -J., Hulthe, J., Wikstrand, J. & Fagerberg, B. Prevalence of diabetes and impaired glucose tolerance in 64-year-old Swedish women: experiences of using repeated oral glucose tolerance tests. Diabetes Care 29, 363–367 (2006).
doi: 10.2337/diacare.29.02.06.dc05-1229 pubmed: 16443888
Feskens, E. J., Bowles, C. H. & Kromhout, D. Intra- and interindividual variability of glucose tolerance in an elderly population. J. Clin. Epidemiol. 44, 947–953 (1991).
doi: 10.1016/0895-4356(91)90058-H pubmed: 1890437
Balion, C. M. et al. Reproducibility of impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) classification: a systematic review. Clin. Chem. Lab. Med. 45, 1180–1185 (2007).
doi: 10.1515/CCLM.2007.505 pubmed: 17635074
Freckmann, G., Pleus, S., Grady, M., Setford, S. & Levy, B. Measures of accuracy for continuous glucose monitoring and blood glucose monitoring devices. J. Diabetes Sci. Technol. 13, 575–583 (2019).
doi: 10.1177/1932296818812062 pubmed: 30453761
Facchinetti, A. Continuous glucose monitoring sensors: past, present and future algorithmic challenges. Sensors 16, 2093 (2016).
doi: 10.3390/s16122093 pubmed: 27941663 pmcid: 5191073
Sacks, D. B. et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin. Chem. 69, 808–868 (2023).
doi: 10.1093/clinchem/hvad080 pubmed: 37473453
Battelino, T. et al. Continuous glucose monitoring and metrics for clinical trials: an international consensus statement. Lancet Diabetes Endocrinol. 11, 42–57 (2023).
doi: 10.1016/S2213-8587(22)00319-9 pubmed: 36493795
Keshet, A. et al. CGMap: characterizing continuous glucose monitor data in thousands of non-diabetic individuals. Cell Metab. 35, 758–769.e3 (2023).
doi: 10.1016/j.cmet.2023.04.002 pubmed: 37080199
Shilo, S. et al. 10K: a large-scale prospective longitudinal study in Israel. Eur. J. Epidemiol. 36, 1187–1194 (2021).
doi: 10.1007/s10654-021-00753-5 pubmed: 33993378
Shah, V. N. et al. Continuous glucose monitoring profiles in healthy nondiabetic participants: a multicenter prospective study. J. Clin. Endocrinol. Metab. 104, 4356–4364 (2019).
doi: 10.1210/jc.2018-02763 pubmed: 31127824 pmcid: 7296129
Jarvis, P. R. E., Cardin, J. L., Nisevich-Bede, P. M. & McCarter, J. P. Continuous glucose monitoring in a healthy population: understanding the post-prandial glycemic response in individuals without diabetes mellitus. Metab. Clin. Exp. 146, 155640 (2023).
doi: 10.1016/j.metabol.2023.155640 pubmed: 37356796
Zeevi, D. et al. Personalized nutrition by prediction of glycemic responses. Cell 163, 1079–1094 (2015).
doi: 10.1016/j.cell.2015.11.001 pubmed: 26590418
Alberti, K. G. M. M. & Zimmet, P. Z. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabet. Med. 15, 539–553 (1998).
doi: 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S pubmed: 9686693
Inzucchi, S. E. Diagnosis of diabetes. N. Engl. J. Med. 367, 542–550 (2012).
doi: 10.1056/NEJMcp1103643 pubmed: 22873534
Kim, J. A. et al. Impact of visit-to-visit fasting plasma glucose variability on the development of type 2 diabetes: a nationwide population-based cohort study. Diabetes Care 41, 2610–2616 (2018).
doi: 10.2337/dc18-0802 pubmed: 30254081
Chang, T. et al. Highly integrated watch for noninvasive continual glucose monitoring. Microsyst. Nanoeng. 8, 25 (2022).
doi: 10.1038/s41378-022-00355-5 pubmed: 35310514 pmcid: 8866463
Hu, Y. et al. Combined use of fasting plasma glucose and glycated hemoglobin A1c in the screening of diabetes and impaired glucose tolerance. Acta Diabetol. 47, 231–236 (2010).
doi: 10.1007/s00592-009-0143-2 pubmed: 19760291
Gao, L. et al. Association between carotid intima-media thickness and fasting blood glucose level: a population-based cross-sectional study among low-income adults in rural China. J. Diabetes Investig. 8, 788–797 (2017).
doi: 10.1111/jdi.12639 pubmed: 28160451 pmcid: 5668475
Rodbard, D. Characterizing accuracy and precision of glucose sensors and meters. J. Diabetes Sci. Technol. 8, 980–985 (2014).
doi: 10.1177/1932296814541810 pubmed: 25037194 pmcid: 4455380
Pleus, S. et al. Rate-of-change dependence of the performance of two cgm systems during induced glucose swings. J. Diabetes Sci. Technol. 9, 801–807 (2015).
doi: 10.1177/1932296815578716 pubmed: 25852074 pmcid: 4525645
Leelarathna, L. & Wilmot, E. G. Flash forward: a review of flash glucose monitoring. Diabet. Med. 35, 472–482 (2018).
doi: 10.1111/dme.13584 pubmed: 29356072
Tsoukas, M. et al. Accuracy of FreeStyle Libre in adults with type 1 diabetes: the effect of sensor age. Diabetes Technol. Ther. 22, 203–207 (2020).
doi: 10.1089/dia.2019.0262 pubmed: 31613140
Yalamanchali, S. et al. Diagnosis of obstructive sleep apnea by peripheral arterial tonometry: meta-analysis. JAMA Otolaryngol. Head. Neck Surg. 139, 1343–1350 (2013).
doi: 10.1001/jamaoto.2013.5338 pubmed: 24158564
DRSplus TrueColor high-resolution confocal fundus camera. iCare https://www.icare-world.com/product/icare-drsplus/ (2024).
Zhou, Y. et al. Automorph: automated retinal vascular morphology quantification via a deep learning pipeline. Transl. Vis. Sci. Technol. 11, 12 (2022).
doi: 10.1167/tvst.11.7.12 pubmed: 35833885 pmcid: 9290317
Levey, A. S. et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of diet in renal disease study group. Ann. Intern. Med. 130, 461–470 (1999).
doi: 10.7326/0003-4819-130-6-199903160-00002 pubmed: 10075613
Seabold, S. & Perktold, J. Statsmodels: econometric and statistical modeling with Python. In Proc. 9th Python in Science Conference 92–96 (SciPy, 2010).
Vallat, R. Pingouin: statistics in Python. JOSS 3, 1026 (2018).
doi: 10.21105/joss.01026

Auteurs

Smadar Shilo (S)

Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.
Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel.

Ayya Keshet (A)

Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.

Hagai Rossman (H)

Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Pheno.AI, Tel-Aviv, Israel.

Anastasia Godneva (A)

Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.

Yeela Talmor-Barkan (Y)

Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel.

Yaron Aviv (Y)

Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel.

Eran Segal (E)

Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel. eran.segal@weizmann.ac.il.
Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel. eran.segal@weizmann.ac.il.

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