TCF1-LEF1 co-expression identifies a multipotent progenitor cell (T
Journal
Nature immunology
ISSN: 1529-2916
Titre abrégé: Nat Immunol
Pays: United States
ID NLM: 100941354
Informations de publication
Date de publication:
08 Apr 2024
08 Apr 2024
Historique:
received:
21
01
2024
accepted:
06
03
2024
medline:
9
4
2024
pubmed:
9
4
2024
entrez:
8
4
2024
Statut:
aheadofprint
Résumé
Repetitive exposure to antigen in chronic infection and cancer drives T cell exhaustion, limiting adaptive immunity. In contrast, aberrant, sustained T cell responses can persist over decades in human allergic disease. To understand these divergent outcomes, we employed bioinformatic, immunophenotyping and functional approaches with human diseased tissues, identifying an abundant population of type 2 helper T (T
Identifiants
pubmed: 38589618
doi: 10.1038/s41590-024-01803-2
pii: 10.1038/s41590-024-01803-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : U.S. Department of Health & Human Services | National Institutes of Health (NIH)
ID : U19AI095219
Organisme : U.S. Department of Health & Human Services | National Institutes of Health (NIH)
ID : T32AI007306
Organisme : U.S. Department of Health & Human Services | National Institutes of Health (NIH)
ID : U19AI095219
Organisme : U.S. Department of Health & Human Services | National Institutes of Health (NIH)
ID : U19AI095219
Organisme : U.S. Department of Health & Human Services | National Institutes of Health (NIH)
ID : U19AI095219
Organisme : U.S. Department of Health & Human Services | National Institutes of Health (NIH)
ID : K23AI139352
Organisme : U.S. Department of Health & Human Services | National Institutes of Health (NIH)
ID : U19AI095219
Organisme : U.S. Department of Health & Human Services | National Institutes of Health (NIH)
ID : U19AI095219
Organisme : U.S. Department of Health & Human Services | National Institutes of Health (NIH)
ID : U19AI095219
Informations de copyright
© 2024. Springer Nature America, Inc.
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