Systematic Review of Heel Puncture-Related Osteomyelitis of the Calcaneus in Newborn Infants.
Bone infection
Calcaneal osteomyelitis
Guthrie test
Heel puncture
Newborn infants
Journal
Infectious diseases and therapy
ISSN: 2193-8229
Titre abrégé: Infect Dis Ther
Pays: New Zealand
ID NLM: 101634499
Informations de publication
Date de publication:
08 Apr 2024
08 Apr 2024
Historique:
received:
19
01
2024
accepted:
06
03
2024
medline:
9
4
2024
pubmed:
9
4
2024
entrez:
8
4
2024
Statut:
aheadofprint
Résumé
Heel puncture (HP) in neonates can result in osteomyelitis if done non-aseptically or with incorrect technique. This study summarizes clinical experience with heel puncture-related osteomyelitis of the calcaneus (HP-CO) in newborns. We systematically reviewed studies that examined HP-CO in newborn patients using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Our search included the PubMed, Embase, and Cochrane Library databases until December 31, 2023. We used the National Institutes of Health (NIH) assessment scale to evaluate the quality of our analyzed studies. This study analyzed 15 neonatal calcaneal osteomyelitis (CO) cases due to HP conducted in six countries from 1976 to 2016. The average age of the cases was 8.87 ± 6.13 days, with an average birth weight of 2367.27 ± 947.59 g. The infants had undergone an average of 9.00 ± 8.90 HP, with 93.33% exhibiting swelling. Staphylococcus aureus was present in 80% of cases. Beta-lactam antibiotics were used, with satisfactory outcomes in 53.33% of cases. However, in seven cases, three patients had flatfoot due to calcaneal deformity, and other complications were observed in some patients after 7-8 years. This study offers valuable insights into a rare condition, including its epidemiology, clinical and laboratory characteristics, and treatment options for infants with HP-CO. To prevent the risk of osteomyelitis in this vulnerable group of patients, increasing awareness and maintaining strict aseptic techniques is necessary. We recommend that infants presenting with tenderness, redness, purulent discharge, erythema, or fever and with a history of repeated HP and swollen ankles should be evaluated for suspicion of osteomyelitis. A graphical abstract is avilable for this article.
Identifiants
pubmed: 38589762
doi: 10.1007/s40121-024-00957-8
pii: 10.1007/s40121-024-00957-8
doi:
Types de publication
Journal Article
Review
Langues
eng
Informations de copyright
© 2024. The Author(s).
Références
Shah VS, Ohlsson A. Venepuncture versus heel lance for blood sampling in term neonates. Cochrane Database Syst Rev. 2011;2011:CD001452. https://doi.org/10.1002/14651858.CD001452 .
doi: 10.1002/14651858.CD001452
pubmed: 21975734
pmcid: 6984677
Mccann MJ, Wells A. Calcaneal osteomyelitis: current treatment concepts. Int J Low Extrem Wounds. 2020;19:230–5. https://doi.org/10.1177/1534734619895187 .
doi: 10.1177/1534734619895187
pubmed: 31852303
Blumenfeld TA, Turi GK, Blanc WA. Recommended site and depth of newborn heel skin punctures based on anatomical measurements and histopathology. Lancet. 1979;1:230–3. https://doi.org/10.1016/s0140-6736(79)90765-7 .
doi: 10.1016/s0140-6736(79)90765-7
pubmed: 84896
The National Institutes of Health (NIH) quality assessment tool for case series studies. 2024. Available at: https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-tools . Accessed July 2021.
Lilien LD, Harris VJ, Ramamurthy RS, Pildes RS. Neonatal osteomyelitis of the calcaneus: complication of heel puncture. J Pediatr. 1976;88:478–80. https://doi.org/10.1016/s0022-3476(76)80272-7 .
doi: 10.1016/s0022-3476(76)80272-7
pubmed: 1245962
Canale ST, Manugian AH. Neonatal osteomyelitis of the os calcis: a complication of repeated heel punctures. Clin Orthop Relat Res. 1981;156:178–82.
doi: 10.1097/00003086-198105000-00024
Abril MJ, Aguilar RL, Albinana CJ. Flatfoot and calcaneal deformity secondary to osteomyelitis after neonatal heel puncture. J Pediatr Orthop B. 1999;8:122–4.
Borris LC, Helleland H. Growth disturbance of the hind part of the foot following osteomyelitis of the calcaneus in the newborn. a report of two cases. J Bone Joint Surg Am. 1986;68:302–5.
doi: 10.2106/00004623-198668020-00019
pubmed: 3944169
Gjurić G, Nikolić E, Benjak V, Mardešić D, Sarnavka V. Osteomyelitis as a complication of capillary blood collection for neonatal screening. Screening. 1992;1:243–7.
doi: 10.1016/0925-6164(92)90040-C
Yuksel S, Yuksel G, Oncel S, Divanli E. Osteomyelitis of the calcaneus in the newborn: an ongoing complication of guthrie test. Eur J Pediatr. 2007;166:503–4. https://doi.org/10.1007/s00431-006-0268-z .
doi: 10.1007/s00431-006-0268-z
pubmed: 17089088
Tural KT, Erat T, Ozdemir H, et al. Calcaneus osteomyelitis secondary to guthrie test: case report. Arch Argent Pediatr. 2016;114:e260–3. https://doi.org/10.5546/aap.2016.eng.e260 .
doi: 10.5546/aap.2016.eng.e260
Goldberg I, Shauer L, Klier I, Seelenfreund M. Neonatal osteomyelitis of the calcaneus following a heel pad puncture: a case report. Clin Orthop Relat Res. 1981;158:195–7.
doi: 10.1097/00003086-198107000-00028
Nadau E, Joseph C, Haraux E, Deroussen F, Gouron R, Klein C. Clinical features and outcomes in children with bone and joint infections of the ankle or foot. Arch Pediatr. 2020;27:464–8. https://doi.org/10.1016/j.arcped.2020.08.005 .
doi: 10.1016/j.arcped.2020.08.005
pubmed: 33011034
Leigh W, Crawford H, Street M, Huang M, Manners S, Puna R. Pediatric calcaneal osteomyelitis. J Pediatr Orthop. 2010;30:888–92. https://doi.org/10.1097/BPO.0b013e3181fa7955 .
doi: 10.1097/BPO.0b013e3181fa7955
pubmed: 21102218
Dich VQ, Nelson JD, Haltalin KC. Osteomyelitis in infants and children. a review of 163 cases. Am J Dis Child. 1975;129:1273–8. https://doi.org/10.1001/archpedi.1975.02120480007004 .
doi: 10.1001/archpedi.1975.02120480007004
pubmed: 1190158
Weissberg ED, Smith AL, Smith DH. Clinical features of neonatal osteomyelitis. Pediatrics. 1974;53:505–10.
doi: 10.1542/peds.53.4.505
pubmed: 4823326