Design, synthesis and in silico molecular docking evaluation of novel 1,2,3-triazole derivatives as potent antimicrobial agents.

1,2,3-Triazoles ADMETlab2.0 Benzooxepines Biological evaluations Chalcones Docking interactions

Journal

Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560

Informations de publication

Date de publication:
15 Apr 2024
Historique:
received: 11 09 2023
revised: 06 03 2024
accepted: 06 03 2024
medline: 9 4 2024
pubmed: 9 4 2024
entrez: 9 4 2024
Statut: epublish

Résumé

Chalcone and triazole scaffolds have demonstrated a crucial role in the advancement of science and technology. Due to their significance, research has proceeded on the design and development of novel benzooxepine connected to 1,2,3-triazolyl chalcone structures. The new chalcone derivatives produced by benzooxepine triazole methyl ketone

Identifiants

DOI: 10.1016/j.heliyon.2024.e27773 PMID: 38590856 PMC: PMC10999864
pubmed: 38590856
doi: 10.1016/j.heliyon.2024.e27773
pii: S2405-8440(24)03804-0
pmc: PMC10999864
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e27773

Informations de copyright

© 2024 The Authors.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

Auteurs

Sudhakar Reddy Baddam (SR)

University of Massachusetts Chan Medical School, RNA Therapeutic Institute, Worcester, MA, 01655, United States.

Mahesh Kumar Avula (MK)

Technology Development Center, Custom Pharmaceutical Services, Dr. Reddy's Laboratories Pvt. Ltd., Hyderabad, Telangana, 500049, India.
Department of Organic Chemistry and FDW, Andhra University, Visakhapatnam, Andhra Pradesh, 530003, India.

Raghunadh Akula (R)

Technology Development Center, Custom Pharmaceutical Services, Dr. Reddy's Laboratories Pvt. Ltd., Hyderabad, Telangana, 500049, India.

Venkateswara Rao Battula (VR)

Department of Chemistry, AU College of Engineering (A), Andhra University, Visakhapatnam, Andhra Pradesh, 530003, India.

Sudhakar Kalagara (S)

Department of Chemistry and Biochemistry, University of the Texas at El Paso, El Paso, TX, 79968, United States.

Ravinder Buchikonda (R)

Technology Development Center, Custom Pharmaceutical Services, Dr. Reddy's Laboratories Pvt. Ltd., Hyderabad, Telangana, 500049, India.

Srinivas Ganta (S)

ScieGen Pharmaceutical Inc., Hauppauge, NY, 11788, United States.

Srinivasadesikan Venkatesan (S)

Department of Chemistry, School of Applied Science and Humanities, VIGNAN's Foundation for Science, Technology and Research, Vadlamudi, Andhra Pradesh, 522213, India.

Tejeswara Rao Allaka (TR)

Centre for Chemical Sciences and Technology, Institute of Science and Technology, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad, Telangana, 500085, India.

Classifications MeSH