Roles of fibroblast growth factors in the treatment of diabetes.

Clinical trials Fibroblast growth factors Metabolic disorders Treatment Type 1 diabetes Type 2 diabetes

Journal

World journal of diabetes
ISSN: 1948-9358
Titre abrégé: World J Diabetes
Pays: United States
ID NLM: 101547524

Informations de publication

Date de publication:
15 Mar 2024
Historique:
received: 18 11 2023
revised: 16 12 2023
accepted: 25 01 2024
medline: 9 4 2024
pubmed: 9 4 2024
entrez: 9 4 2024
Statut: ppublish

Résumé

Diabetes affects about 422 million people worldwide, causing 1.5 million deaths each year. However, the incidence of diabetes is increasing, including several types of diabetes. Type 1 diabetes (5%-10% of diabetic cases) and type 2 diabetes (90%-95% of diabetic cases) are the main types of diabetes in the clinic. Accumulating evidence shows that the fibroblast growth factor (FGF) family plays important roles in many metabolic disorders, including type 1 and type 2 diabetes. FGF consists of 23 family members (FGF-1-23) in humans. Here, we review current findings of FGFs in the treatment of diabetes and management of diabetic complications. Some FGFs (

Identifiants

pubmed: 38591079
doi: 10.4239/wjd.v15.i3.392
pmc: PMC10999039
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

392-402

Informations de copyright

©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: The authors have no conflicts of interest to declare.

Auteurs

Chun-Ye Zhang (CY)

Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, United States.

Ming Yang (M)

Department of Surgery, University of Missouri, Columbia, MO 65212, United States.
NextGen Precision Health Institution, University of Missouri, Columbia, MO 65212, United States. yangmin@health.missouri.edu.

Classifications MeSH