Blood Whispers: Exploring Hematologic Indicators for Diagnosing and Predicting Severity of Vogt-Koyanagi-Harada Syndrome.

Indocyanine green angiography score Vogt-Koyanagi-Harada disease lymphopenia neutrophil to lymphocyte ratio systemic immune-inflammation index

Journal

Ocular immunology and inflammation
ISSN: 1744-5078
Titre abrégé: Ocul Immunol Inflamm
Pays: England
ID NLM: 9312169

Informations de publication

Date de publication:
09 Apr 2024
Historique:
medline: 9 4 2024
pubmed: 9 4 2024
entrez: 9 4 2024
Statut: aheadofprint

Résumé

To investigate the association of clinical findings and indocyanine green angiography (ICGA) score with inflammatory markers derived from complete blood count (CBC) parameters in patients with Vogt-Koyanagi-Harada (VKH) to determine the diagnostic and predictive role. Demographic characteristics, presenting complaints, ocular findings, optical coherence tomography findings, ICGA scores and best corrected visual acuity were recorded in treatment-naive VKH patients at presentation. Patients were divided into two groups as acute stage and chronic recurrent stage. CBC parameters were noted in patients at presentation and healthy controls (HC, Thirty-two patients with VKH (23 females/9 males) with a mean age of 34.1 ± 14.6 years were included in the study. There was an increase in neutrophil count, NLR and SII in patients with VKH compared to HC ( CBC-derived inflammatory parameters indicate that VKH is a systemic inflammation. These parameters can be used in the diagnosis and determination of disease severity of VKH.

Identifiants

pubmed: 38592364
doi: 10.1080/09273948.2024.2334793
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-9

Auteurs

Berru Yargi-Ozkocak (B)

Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, Istanbul, Turkey.

Cigdem Altan (C)

Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, Istanbul, Turkey.

Burcu Kemer-Atik (B)

Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, Istanbul, Turkey.

Berna Basarir (B)

Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, Istanbul, Turkey.

Muhittin Taskapili (M)

Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, Istanbul, Turkey.

Classifications MeSH