Duration of maternally derived antibodies of porcine parvovirus in growing pigs and presence of antibodies in gilts and sows vaccinated with three different parvovirus vaccines.
ELISA
Haemagglutination inhibition test
Maternally derived antibodies
Porcine parvovirus
Seroconversion
Sows
Journal
Porcine health management
ISSN: 2055-5660
Titre abrégé: Porcine Health Manag
Pays: England
ID NLM: 101684126
Informations de publication
Date de publication:
09 Apr 2024
09 Apr 2024
Historique:
received:
10
11
2023
accepted:
06
02
2024
medline:
10
4
2024
pubmed:
10
4
2024
entrez:
9
4
2024
Statut:
epublish
Résumé
While gilts and sows are regularly vaccinated against the porcine parvovirus (PPV), little is known on the presence of antibodies in vaccinated sows nor the decline of maternally derived antibodies (MDA) in their offspring. On twelve farms serum samples were taken from 180 gilts and sows vaccinated at least twice with one of three different commercial PPV vaccines. On nine farms, additional 270 serum samples were collected from growing pigs of three different age categories. All 450 samples were examined for PPV antibodies (Abs) by ELISA and haemagglutination inhibition (HI) assay. In total, 65% of all gilts vaccinated twice with either vaccine 1 or vaccine 3 were seronegative by HI assay. In each farm, there were at least three animals with high Ab titres (≥ 1:1280) indicating the presence of PPV in all twelve study farms. However, PPV DNA could not be detected in collected faecal samples. While low to moderately high Ab titres (1:10-1:640) were measured in 98% of twelve-weeks-old pigs, ELISA was only positive in 30% of the same pigs. Though, the statement on the duration of MDA may depend on the applied test, we could confirm an exponential decay of MDA. In addition, we could demonstrate that applied serological tools are insufficient for the confirmation of successful vaccination.
Identifiants
pubmed: 38594736
doi: 10.1186/s40813-024-00361-1
pii: 10.1186/s40813-024-00361-1
doi:
Types de publication
Journal Article
Langues
eng
Pagination
15Informations de copyright
© 2024. The Author(s).
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