Thrombophilia testing in the era of direct oral anticoagulants.
APS
DOAC
DOAC-Stop
VTE
antiphospholipid syndrome
direct oral anticoagulants
thrombophilia
thrombophilia testing
venous thromboembolism
Journal
Clinical medicine (London, England)
ISSN: 1473-4893
Titre abrégé: Clin Med (Lond)
Pays: England
ID NLM: 101092853
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
medline:
1
9
2021
pubmed:
1
9
2021
entrez:
10
4
2024
Statut:
ppublish
Résumé
Venous thromboembolism (VTE) is increasingly recognised in primary and secondary care practice. The arrival of direct oral anticoagulants (DOACs) has made the management of VTE easier and more convenient. Some patients established on DOACs may need screening for underlying thrombophilias as certain thrombophilic conditions are known to confer a higher thrombosis risk, although the guidelines for when and how to test for a thrombophilia, especially in a patient taking a DOAC, are unclear. This literature review aims to examine when thrombophilia screening should take place in a patient already taking a DOAC, the effect of DOACs on thrombophilia tests, and analyse whether DOACs are safe and effective in both inherited and acquired thrombophilias.
Identifiants
pubmed: 38594851
pii: S1470-2118(24)03068-9
doi: 10.7861/clinmed.2020-1008
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e487-e491Informations de copyright
Copyright © 2021 © 2021 THE AUTHORS. Published by Elsevier Limited on behalf of the Royal College of Physicians. Published by Elsevier Ltd.. All rights reserved.