Evaluating pediatric ureteropelvic junction obstruction: Dynamic magnetic resonance urography

Dynamic contrast-enhanced magnetic resonance urography Magnetic resonance imaging Scintigraphy 99m-technetium mercaptoacetyltriglycine Uteropelvic junction obstruction

Journal

World journal of radiology
ISSN: 1949-8470
Titre abrégé: World J Radiol
Pays: United States
ID NLM: 101538184

Informations de publication

Date de publication:
28 Mar 2024
Historique:
received: 20 11 2023
revised: 18 01 2024
accepted: 12 03 2024
medline: 10 4 2024
pubmed: 10 4 2024
entrez: 10 4 2024
Statut: ppublish

Résumé

Ureteropelvic junction obstruction (UPJO) is a common congenital urinary tract disorder in children. It can be diagnosed as early as To evaluate the discrepancy between dynamic contrast-enhanced magnetic resonance urography (dMRU) and scintigraphy 99m-technetium mercaptoacetyltriglycine (MAG-3) for the functional evaluation of UPJO. Between 2016 and 2020, 126 patients with UPJO underwent surgery at Robert Debré Hospital. Of these, 83 received a prenatal diagnosis, and 43 were diagnosed during childhood. Four of the 126 patients underwent surgery based on the clinical situation and postnatal ultrasound findings without undergoing functional imaging evaluation. Split renal function was evaluated preoperatively using scintigraphy MAG-3 ( The split renal function between the two kidneys was compared in 40 patients (28 boys and 12 girls) using scintigraphy MAG-3 and dMRU. Differential renal function, as determined using both modalities, showed a difference of < 10% in 31 children and > 10% in 9 children. Calculation of the relative renal function using dMRU revealed an excellent correlation coefficient with renal scintigraphy MAG-3 for both kidneys. Our findings demonstrated that dMRU is equivalent to scintigraphy MAG-3 for evaluating split renal function in patients with UPJO.

Sections du résumé

BACKGROUND BACKGROUND
Ureteropelvic junction obstruction (UPJO) is a common congenital urinary tract disorder in children. It can be diagnosed as early as
AIM OBJECTIVE
To evaluate the discrepancy between dynamic contrast-enhanced magnetic resonance urography (dMRU) and scintigraphy 99m-technetium mercaptoacetyltriglycine (MAG-3) for the functional evaluation of UPJO.
METHODS METHODS
Between 2016 and 2020, 126 patients with UPJO underwent surgery at Robert Debré Hospital. Of these, 83 received a prenatal diagnosis, and 43 were diagnosed during childhood. Four of the 126 patients underwent surgery based on the clinical situation and postnatal ultrasound findings without undergoing functional imaging evaluation. Split renal function was evaluated preoperatively using scintigraphy MAG-3 (
RESULTS RESULTS
The split renal function between the two kidneys was compared in 40 patients (28 boys and 12 girls) using scintigraphy MAG-3 and dMRU. Differential renal function, as determined using both modalities, showed a difference of < 10% in 31 children and > 10% in 9 children. Calculation of the relative renal function using dMRU revealed an excellent correlation coefficient with renal scintigraphy MAG-3 for both kidneys.
CONCLUSION CONCLUSIONS
Our findings demonstrated that dMRU is equivalent to scintigraphy MAG-3 for evaluating split renal function in patients with UPJO.

Identifiants

pubmed: 38596171
doi: 10.4329/wjr.v16.i3.49
pmc: PMC10999956
doi:

Types de publication

Journal Article

Langues

eng

Pagination

49-57

Informations de copyright

©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Auteurs

Yousuf Al-Shaqsi (Y)

Department of Pediatric Surgery, Sultan Qaboos University Hospital, Muscat 123, Oman.
Service de Chirurgie Viscérale et Urologie Pédiatrique, Hôpital Universitaire Robert-Debré, Assistance-Publique Hôpitaux de Paris, Paris 75019, France.
Centre de Références Maladies Rares, Malformations Rares des Voies Urinaires (MARVU), Paris 97019, France. y.alshaqsi@hotmail.com.

Matthieu Peycelon (M)

Service de Chirurgie Viscérale et Urologie Pédiatrique, Hôpital Universitaire Robert-Debré, Assistance-Publique Hôpitaux de Paris, Paris 75019, France.
Centre de Références Maladies Rares, Malformations Rares des Voies Urinaires (MARVU), Paris 97019, France.
Faculté de Médecine, Université de Paris, Paris 75006, France.

Annabel Paye-Jaouen (A)

Service de Chirurgie Viscérale et Urologie Pédiatrique, Hôpital Universitaire Robert-Debré, Assistance-Publique Hôpitaux de Paris, Paris 75019, France.
Centre de Références Maladies Rares, Malformations Rares des Voies Urinaires (MARVU), Paris 97019, France.

Elisabeth Carricaburu (E)

Service de Chirurgie Viscérale et Urologie Pédiatrique, Hôpital Universitaire Robert-Debré, Assistance-Publique Hôpitaux de Paris, Paris 75019, France.

Anca Tanase (A)

Centre de Références Maladies Rares, Malformations Rares des Voies Urinaires (MARVU), Paris 97019, France.
Service d'Imagerie Pédiatrique, Hôpital Universitaire Robert-Debré, Assistance-Publique Hôpitaux de Paris, Paris 75019, France.

Christine Grapin-Dagorno (C)

Service de Chirurgie Viscérale et Urologie Pédiatrique, Hôpital Universitaire Robert-Debré, Assistance-Publique Hôpitaux de Paris, Paris 75019, France.
Université Paris 13, Sorbonne Paris Cité, Paris 75013, France.

Alaa El-Ghoneimi (A)

Service de Chirurgie Viscérale et Urologie Pédiatrique, Hôpital Universitaire Robert-Debré, Assistance-Publique Hôpitaux de Paris, Paris 75019, France.
Centre de Références Maladies Rares, Malformations Rares des Voies Urinaires (MARVU), Paris 97019, France.
Faculté de Médecine, Université de Paris, Paris 75006, France.

Classifications MeSH