Evaluation of vascular aging on measures of cardiac function and mechanical efficiency: insights from
aortic compliance
computational model
end-systolic pressure-volume relationship
mechanical efficiency
pressure-volume area
stroke work
vascular aging
ventricular-vascular coupling
Journal
Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388
Informations de publication
Date de publication:
2024
2024
Historique:
received:
06
12
2023
accepted:
23
01
2024
medline:
11
4
2024
pubmed:
11
4
2024
entrez:
11
4
2024
Statut:
epublish
Résumé
This study evaluated the hypothesis that vascular aging (VA) reduces ventricular contractile function and mechanical efficiency (ME) using the left ventricular pressure-volume (PV) construct. A previously published In phase I, EDV and ESV increased, as did SW and PVA. The impact on the CS parameters demonstrated a small decrease in ESPVR, no change in The CM generated new insights regarding how the VA process impacts the contractile state of the myocardium and ME.
Identifiants
pubmed: 38601041
doi: 10.3389/fcvm.2024.1351484
pmc: PMC11004371
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1351484Informations de copyright
© 2024 Mulligan, Thrash, Mitrev, Folk, Exarchakis, Ewert and Hill.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.