Esm-1 mediates transcriptional polarization associated with diabetic kidney disease.

Diabetic kidney disease Diabetic nephropathy Endothelial cell-specific molecule-1 Inflammation Single-cell RNA

Journal

American journal of physiology. Renal physiology
ISSN: 1522-1466
Titre abrégé: Am J Physiol Renal Physiol
Pays: United States
ID NLM: 100901990

Informations de publication

Date de publication:
11 Apr 2024
Historique:
medline: 11 4 2024
pubmed: 11 4 2024
entrez: 11 4 2024
Statut: aheadofprint

Résumé

Esm-1, endothelial cell-specific molecule-1, is a susceptibility gene for diabetic kidney disease (DKD) and is a secreted proteoglycan, with notable expression in kidney, which attenuates inflammation and albuminuria. However

Identifiants

DOI: 10.1152/ajprenal.00419.2023 PMID: 38601985
pubmed: 38601985
doi: 10.1152/ajprenal.00419.2023
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK115770
Pays : United States

Auteurs

Alexandre Gaudet (A)

Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, France.

Xiaoyi Zheng (X)

Division of Nephrology, Stanford University School of Medicine, Stanford, United States.

Neeraja Kambham (N)

Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.

Vivek Bhalla (V)

Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States.

Classifications MeSH